diff --git a/src/pages/home/report/ReactionList/PopoverReactionList/index.js b/src/pages/home/report/ReactionList/PopoverReactionList/index.js
index c39eeddb7fd..32788524984 100644
--- a/src/pages/home/report/ReactionList/PopoverReactionList/index.js
+++ b/src/pages/home/report/ReactionList/PopoverReactionList/index.js
@@ -29,7 +29,19 @@ function PopoverReactionList(props) {
         innerReactionListRef.current.showReactionList(event, reactionListAnchor);
     };
 
-    useImperativeHandle(props.innerRef, () => ({showReactionList}), []);
+    const hideReactionList = () => {
+        innerReactionListRef.current.hideReactionList();
+    };
+
+    /**
+     * Whether PopoverReactionList is active for the Report Action.
+     *
+     * @param {Number|String} actionID
+     * @return {Boolean}
+     */
+    const isActiveReportAction = (actionID) => Boolean(actionID) && reactionListReportActionID === actionID;
+
+    useImperativeHandle(props.innerRef, () => ({showReactionList, hideReactionList, isActiveReportAction}));
 
     return (
         <BasePopoverReactionList
diff --git a/src/pages/home/report/ReportActionItem.js b/src/pages/home/report/ReportActionItem.js
index aa793580e3a..845a2bc75ed 100644
--- a/src/pages/home/report/ReportActionItem.js
+++ b/src/pages/home/report/ReportActionItem.js
@@ -1,6 +1,6 @@
 import _ from 'underscore';
 import lodashGet from 'lodash/get';
-import React, {useState, useRef, useEffect, memo, useCallback} from 'react';
+import React, {useState, useRef, useEffect, memo, useCallback, useContext} from 'react';
 import {InteractionManager, View} from 'react-native';
 import PropTypes from 'prop-types';
 import {withOnyx} from 'react-native-onyx';
@@ -64,6 +64,7 @@ import * as PersonalDetailsUtils from '../../../libs/PersonalDetailsUtils';
 import ReportActionItemBasicMessage from './ReportActionItemBasicMessage';
 import * as store from '../../../libs/actions/ReimbursementAccount/store';
 import * as BankAccounts from '../../../libs/actions/BankAccounts';
+import ReportScreenContext from '../ReportScreenContext';
 import Permissions from '../../../libs/Permissions';
 
 const propTypes = {
@@ -126,15 +127,15 @@ function ReportActionItem(props) {
     const [isContextMenuActive, setIsContextMenuActive] = useState(ReportActionContextMenu.isActiveReportAction(props.action.reportActionID));
     const [isHidden, setIsHidden] = useState(false);
     const [moderationDecision, setModerationDecision] = useState(CONST.MODERATION.MODERATOR_DECISION_APPROVED);
+    const {reactionListRef} = useContext(ReportScreenContext);
     const textInputRef = useRef();
     const popoverAnchorRef = useRef();
     const downloadedPreviews = useRef([]);
 
     useEffect(
         () => () => {
-            // ReportActionContextMenu and EmojiPicker are global component,
-            // we use showContextMenu and showEmojiPicker to show them,
-            // so we should also hide them when the current component is destroyed
+            // ReportActionContextMenu, EmojiPicker and PopoverReactionList are global components,
+            // we should also hide them when the current component is destroyed
             if (ReportActionContextMenu.isActiveReportAction(props.action.reportActionID)) {
                 ReportActionContextMenu.hideContextMenu();
                 ReportActionContextMenu.hideDeleteModal();
@@ -142,8 +143,11 @@ function ReportActionItem(props) {
             if (EmojiPickerAction.isActiveReportAction(props.action.reportActionID)) {
                 EmojiPickerAction.hideEmojiPicker(true);
             }
+            if (reactionListRef.current && reactionListRef.current.isActiveReportAction(props.action.reportActionID)) {
+                reactionListRef.current.hideReactionList();
+            }
         },
-        [props.action.reportActionID],
+        [props.action.reportActionID, reactionListRef],
     );
 
     const isDraftEmpty = !props.draftMessage;