diff --git a/lighthouse-cli/test/cli/__snapshots__/index-test.js.snap b/lighthouse-cli/test/cli/__snapshots__/index-test.js.snap
index 99477122af86..c10207aa4b0e 100644
--- a/lighthouse-cli/test/cli/__snapshots__/index-test.js.snap
+++ b/lighthouse-cli/test/cli/__snapshots__/index-test.js.snap
@@ -255,9 +255,15 @@ Object {
     Object {
       "path": "accessibility/duplicate-id-aria",
     },
+    Object {
+      "path": "accessibility/empty-table-header",
+    },
     Object {
       "path": "accessibility/form-field-multiple-labels",
     },
+    Object {
+      "path": "accessibility/frame-focusable-content",
+    },
     Object {
       "path": "accessibility/frame-title",
     },
@@ -588,11 +594,21 @@ Object {
           "id": "duplicate-id-aria",
           "weight": 10,
         },
+        Object {
+          "group": "a11y-tables-lists",
+          "id": "empty-table-header",
+          "weight": 2,
+        },
         Object {
           "group": "a11y-names-labels",
           "id": "form-field-multiple-labels",
           "weight": 2,
         },
+        Object {
+          "group": "a11y-navigation",
+          "id": "frame-focusable-content",
+          "weight": 3,
+        },
         Object {
           "group": "a11y-names-labels",
           "id": "frame-title",
diff --git a/lighthouse-cli/test/fixtures/a11y/a11y_tester.html b/lighthouse-cli/test/fixtures/a11y/a11y_tester.html
index 9e997fcb3e90..754ef479d29b 100644
--- a/lighthouse-cli/test/fixtures/a11y/a11y_tester.html
+++ b/lighthouse-cli/test/fixtures/a11y/a11y_tester.html
@@ -135,12 +135,24 @@
       <div id="duplicate-id-aria"></div>
       <input type="text" aria-labelledby="duplicate-id-aria"/>
     </section>
+    <p>empty-table-header</p>
+    <section>
+      <table>
+        <tr>
+          <th></th>
+        </tr>
+      </table>
+    </section>
     <p>form-field-multiple-labels</p>
     <section>
       <label for="form-field-multiple-labels" id="label1">label1</label>
       <label for="form-field-multiple-labels">label2</label>
       <input type="checkbox" id="form-field-multiple-labels" />
     </section>
+    <p>frame-focusable-content</p>
+    <section>
+      <iframe title="some title" tabindex="-1" src="../dobetterweb/focusable-iframe.html"></iframe>
+    </section>
     <p>frame-title</p>
     <section>
       <iframe id="frame-title"></iframe>
diff --git a/lighthouse-cli/test/fixtures/dobetterweb/dbw_tester.html b/lighthouse-cli/test/fixtures/dobetterweb/dbw_tester.html
index 7886b840fe4a..d319ce54a526 100644
--- a/lighthouse-cli/test/fixtures/dobetterweb/dbw_tester.html
+++ b/lighthouse-cli/test/fixtures/dobetterweb/dbw_tester.html
@@ -227,6 +227,15 @@ <h2>Do better web tester page</h2>
 <button class="small-button">Do something</button>
 <button class="small-button">Do something else</button>
 
+<!-- FAIL - frame-focusable-content -->
+<iframe tabindex="-1" src="focusable-iframe.html"></iframe>
+<!-- FAIL - empty-table-header -->
+<table>
+  <tr>
+    <th></th>
+  </tr>
+</table>
+
 <!-- Some websites overwrite the original Error object. The captureJSCallUsage function
   relies on the native Error object and prepareStackTrace from V8. When overwriting the stack
   property the e.stack inside the gatherer won't be in the correct format
diff --git a/lighthouse-cli/test/fixtures/dobetterweb/focusable-iframe.html b/lighthouse-cli/test/fixtures/dobetterweb/focusable-iframe.html
new file mode 100644
index 000000000000..84d5ca7a5a7d
--- /dev/null
+++ b/lighthouse-cli/test/fixtures/dobetterweb/focusable-iframe.html
@@ -0,0 +1 @@
+<a href='/'>Home</a>
diff --git a/lighthouse-cli/test/smokehouse/test-definitions/a11y.js b/lighthouse-cli/test/smokehouse/test-definitions/a11y.js
index c7d29fa57297..0f61c64fa98c 100644
--- a/lighthouse-cli/test/smokehouse/test-definitions/a11y.js
+++ b/lighthouse-cli/test/smokehouse/test-definitions/a11y.js
@@ -476,7 +476,7 @@ const expectations = {
               node: {
                 'type': 'node',
                 'selector': 'body > section > input#form-field-multiple-labels',
-                'path': '2,HTML,1,BODY,43,SECTION,2,INPUT',
+                'path': '2,HTML,1,BODY,45,SECTION,2,INPUT',
                 'snippet': '<input type="checkbox" id="form-field-multiple-labels">',
                 'explanation': 'Fix all of the following:\n  Multiple label elements is not widely supported in assistive technologies. Ensure the first label contains all necessary information.',
                 'nodeLabel': 'body > section > input#form-field-multiple-labels',
@@ -487,7 +487,7 @@ const expectations = {
                   {
                     relatedNode: {
                       'type': 'node',
-                      'path': '2,HTML,1,BODY,43,SECTION,0,LABEL',
+                      'path': '2,HTML,1,BODY,45,SECTION,0,LABEL',
                       'selector': 'body > section > label#label1',
                       'snippet': '<label for="form-field-multiple-labels" id="label1">',
                       'nodeLabel': 'label1',
@@ -496,7 +496,7 @@ const expectations = {
                   {
                     relatedNode: {
                       'type': 'node',
-                      'path': '2,HTML,1,BODY,43,SECTION,1,LABEL',
+                      'path': '2,HTML,1,BODY,45,SECTION,1,LABEL',
                       'selector': 'body > section > label',
                       'snippet': '<label for="form-field-multiple-labels">',
                       'nodeLabel': 'label2',
@@ -532,7 +532,7 @@ const expectations = {
               node: {
                 'type': 'node',
                 'selector': 'body > section > h3',
-                'path': '2,HTML,1,BODY,47,SECTION,1,H3',
+                'path': '2,HTML,1,BODY,51,SECTION,1,H3',
                 'snippet': '<h3>',
                 'explanation': 'Fix any of the following:\n  Heading order invalid',
                 'nodeLabel': 'sub-sub-header',
@@ -751,6 +751,27 @@ const expectations = {
           ],
         },
       },
+      'frame-focusable-content': {
+        score: null,
+        scoreDisplayMode: 'notApplicable',
+      },
+      'empty-table-header': {
+        score: null,
+        details: {
+          items: [
+            {
+              node: {
+                'type': 'node',
+                'selector': 'table > tbody > tr > th',
+                'path': '2,HTML,1,BODY,43,SECTION,0,TABLE,0,TBODY,0,TR,0,TH',
+                'snippet': '<th>',
+                'explanation': 'Fix any of the following:\n  Element does not have text that is visible to screen readers',
+                'nodeLabel': 'table > tbody > tr > th',
+              },
+            },
+          ],
+        },
+      },
     },
   },
 };
diff --git a/lighthouse-cli/test/smokehouse/test-definitions/dobetterweb.js b/lighthouse-cli/test/smokehouse/test-definitions/dobetterweb.js
index fab2fcc12fe0..e6876b08bc40 100644
--- a/lighthouse-cli/test/smokehouse/test-definitions/dobetterweb.js
+++ b/lighthouse-cli/test/smokehouse/test-definitions/dobetterweb.js
@@ -391,11 +391,11 @@ const expectations = {
       },
       'dom-size': {
         score: 1,
-        numericValue: 153,
+        numericValue: 158,
         details: {
           items: [
-            {statistic: 'Total DOM Elements', value: 153},
-            {statistic: 'Maximum DOM Depth', value: 4},
+            {statistic: 'Total DOM Elements', value: 158},
+            {statistic: 'Maximum DOM Depth', value: 5},
             {
               statistic: 'Maximum Child Elements',
               value: 100,
diff --git a/lighthouse-core/audits/accessibility/empty-table-header.js b/lighthouse-core/audits/accessibility/empty-table-header.js
new file mode 100644
index 000000000000..79aff530d45c
--- /dev/null
+++ b/lighthouse-core/audits/accessibility/empty-table-header.js
@@ -0,0 +1,44 @@
+/**
+ * @license Copyright 2021 The Lighthouse Authors. All Rights Reserved.
+ * Licensed under the Apache License, Version 2.0 (the "License"); you may not use this file except in compliance with the License. You may obtain a copy of the License at http://www.apache.org/licenses/LICENSE-2.0
+ * Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License.
+ */
+'use strict';
+
+/**
+ * @fileoverview Ensures table headers have discernible text.
+ * See base class in axe-audit.js for audit() implementation.
+ */
+
+const AxeAudit = require('./axe-audit.js');
+const i18n = require('../../lib/i18n/i18n.js');
+
+const UIStrings = {
+  /** Title of an accesibility audit that checks if there are any table headers without visible text. This title is descriptive of the successful state and is shown to users when no user action is required. */
+  title: '`table` headers have visible text',
+  /** Title of an accesibility audit that checks if there are any table headers without visible text. This title is descriptive of the failing state and is shown to users when there is a failure that needs to be addressed. */
+  failureTitle: '`table` headers do not have visible text',
+  /** Description of a Lighthouse audit that tells the user *why* they should try to pass. This is displayed after a user expands the section to see more. No character length limits. 'Learn More' becomes link text to additional documentation. */
+  description: '`table` headers should have visible text so assistive technologies like screen readers may describe table contents appropriately. [Learn more](https://dequeuniversity.com/rules/axe/4.2/empty-table-header).',
+};
+
+const str_ = i18n.createMessageInstanceIdFn(__filename, UIStrings);
+
+class EmptyTableHeader extends AxeAudit {
+  /**
+   * @return {LH.Audit.Meta}
+   */
+  static get meta() {
+    return {
+      id: 'empty-table-header',
+      title: str_(UIStrings.title),
+      failureTitle: str_(UIStrings.failureTitle),
+      description: str_(UIStrings.description),
+      scoreDisplayMode: AxeAudit.SCORING_MODES.INFORMATIVE,
+      requiredArtifacts: ['Accessibility'],
+    };
+  }
+}
+
+module.exports = EmptyTableHeader;
+module.exports.UIStrings = UIStrings;
diff --git a/lighthouse-core/audits/accessibility/frame-focusable-content.js b/lighthouse-core/audits/accessibility/frame-focusable-content.js
new file mode 100644
index 000000000000..1efed50a9087
--- /dev/null
+++ b/lighthouse-core/audits/accessibility/frame-focusable-content.js
@@ -0,0 +1,43 @@
+/**
+ * @license Copyright 2021 The Lighthouse Authors. All Rights Reserved.
+ * Licensed under the Apache License, Version 2.0 (the "License"); you may not use this file except in compliance with the License. You may obtain a copy of the License at http://www.apache.org/licenses/LICENSE-2.0
+ * Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License.
+ */
+'use strict';
+
+/**
+ * @fileoverview No `<iframe tabindex=-1>` has focusable content.
+ * See base class in axe-audit.js for audit() implementation.
+ */
+
+const AxeAudit = require('./axe-audit.js');
+const i18n = require('../../lib/i18n/i18n.js');
+
+const UIStrings = {
+  /** Title of an accesibility audit that checks if there are any iframes with focusable content that mistakenly set tabindex = -1. This title is descriptive of the successful state and is shown to users when no user action is required. */
+  title: '`<iframe>` elements with focusable content do not have a negative `tabindex`',
+  /** Title of an accesibility audit that checks if there are any iframes with focusable content that mistakently set tabindex = -1. This title is descriptive of the failing state and is shown to users when there is a failure that needs to be addressed. */
+  failureTitle: '`<iframe>` elements with focusable content have a negative `tabindex`',
+  /** Description of a Lighthouse audit that tells the user *why* they should try to pass. This is displayed after a user expands the section to see more. No character length limits. 'Learn More' becomes link text to additional documentation. */
+  description: 'Focusable elements within an `<iframe>` element with a negative `tabindex` cannot be reached via keyboard navigation. [Learn more](https://dequeuniversity.com/rules/axe/4.2/frame-focusable-content).',
+};
+
+const str_ = i18n.createMessageInstanceIdFn(__filename, UIStrings);
+
+class FrameFocusableContent extends AxeAudit {
+  /**
+   * @return {LH.Audit.Meta}
+   */
+  static get meta() {
+    return {
+      id: 'frame-focusable-content',
+      title: str_(UIStrings.title),
+      failureTitle: str_(UIStrings.failureTitle),
+      description: str_(UIStrings.description),
+      requiredArtifacts: ['Accessibility'],
+    };
+  }
+}
+
+module.exports = FrameFocusableContent;
+module.exports.UIStrings = UIStrings;
diff --git a/lighthouse-core/config/default-config.js b/lighthouse-core/config/default-config.js
index 8f73f964cb30..4ff54d35735f 100644
--- a/lighthouse-core/config/default-config.js
+++ b/lighthouse-core/config/default-config.js
@@ -256,7 +256,9 @@ const defaultConfig = {
     'accessibility/document-title',
     'accessibility/duplicate-id-active',
     'accessibility/duplicate-id-aria',
+    'accessibility/empty-table-header',
     'accessibility/form-field-multiple-labels',
+    'accessibility/frame-focusable-content',
     'accessibility/frame-title',
     'accessibility/heading-order',
     'accessibility/html-has-lang',
@@ -516,7 +518,9 @@ const defaultConfig = {
         {id: 'document-title', weight: 3, group: 'a11y-names-labels'},
         {id: 'duplicate-id-active', weight: 3, group: 'a11y-navigation'},
         {id: 'duplicate-id-aria', weight: 10, group: 'a11y-aria'},
+        {id: 'empty-table-header', weight: 2, group: 'a11y-tables-lists'},
         {id: 'form-field-multiple-labels', weight: 2, group: 'a11y-names-labels'},
+        {id: 'frame-focusable-content', weight: 3, group: 'a11y-navigation'},
         {id: 'frame-title', weight: 3, group: 'a11y-names-labels'},
         {id: 'heading-order', weight: 2, group: 'a11y-navigation'},
         {id: 'html-has-lang', weight: 3, group: 'a11y-language'},
diff --git a/lighthouse-core/gather/gatherers/accessibility.js b/lighthouse-core/gather/gatherers/accessibility.js
index 178ca46b763b..e1cf7f35ecdb 100644
--- a/lighthouse-core/gather/gatherers/accessibility.js
+++ b/lighthouse-core/gather/gatherers/accessibility.js
@@ -57,9 +57,9 @@ async function runA11yChecks() {
       'svg-img-alt': {enabled: false},
       'audio-caption': {enabled: false},
       'aria-treeitem-name': {enabled: true},
+      'empty-table-header': {enabled: true},
       // https://github.com/dequelabs/axe-core/issues/2958
       'nested-interactive': {enabled: false},
-      'frame-focusable-content': {enabled: false},
     },
   });
 
diff --git a/lighthouse-core/test/fraggle-rock/scenarios/api-test-pptr.js b/lighthouse-core/test/fraggle-rock/scenarios/api-test-pptr.js
index e4b9ca06a2f3..298c7e6780b7 100644
--- a/lighthouse-core/test/fraggle-rock/scenarios/api-test-pptr.js
+++ b/lighthouse-core/test/fraggle-rock/scenarios/api-test-pptr.js
@@ -47,7 +47,7 @@ describe('Fraggle Rock API', () => {
 
       const {auditResults, erroredAudits, failedAudits} = getAuditsBreakdown(lhr);
       // TODO(FR-COMPAT): This assertion can be removed when full compatibility is reached.
-      expect(auditResults.length).toMatchInlineSnapshot(`73`);
+      expect(auditResults.length).toMatchInlineSnapshot(`75`);
 
       expect(erroredAudits).toHaveLength(0);
       expect(failedAudits.map(audit => audit.id)).toContain('label');
@@ -147,7 +147,7 @@ describe('Fraggle Rock API', () => {
       const {lhr} = result;
       const {auditResults, failedAudits, erroredAudits} = getAuditsBreakdown(lhr);
       // TODO(FR-COMPAT): This assertion can be removed when full compatibility is reached.
-      expect(auditResults.length).toMatchInlineSnapshot(`152`);
+      expect(auditResults.length).toMatchInlineSnapshot(`154`);
       expect(erroredAudits).toHaveLength(0);
 
       const failedAuditIds = failedAudits.map(audit => audit.id);
diff --git a/lighthouse-core/test/results/artifacts/artifacts.json b/lighthouse-core/test/results/artifacts/artifacts.json
index 7dbf2543022e..645ba10c1db3 100644
--- a/lighthouse-core/test/results/artifacts/artifacts.json
+++ b/lighthouse-core/test/results/artifacts/artifacts.json
@@ -1769,6 +1769,37 @@
             "isBlockCoverage": false
           }
         ]
+      },
+      {
+        "id": "empty-table-header",
+        "impact": "minor",
+        "tags": [
+          "wcag131",
+          "cat.aria"
+        ],
+        "nodes": [
+          {
+            "target": [
+              "th"
+            ],
+            "failureSummary": "Fix any of the following:\n  Unable to determine if element has children",
+            "node": {
+              "lhId": "6-44-TH",
+              "devtoolsNodePath": "3,HTML,1,BODY,34,TABLE,0,TBODY,0,TR,0,TH",
+              "selector": "table > tbody > tr > th",
+              "boundingRect": {
+                "top": 1328,
+                "bottom": 1330,
+                "left": 10,
+                "right": 12,
+                "width": 2,
+                "height": 2
+              },
+              "snippet": "<th>",
+              "nodeLabel": "th"
+            }
+          }
+        ]
       }
     ],
     "http://localhost:10200/dobetterweb/third_party/aggressive-promise-polyfill.js": [
@@ -11687,6 +11718,42 @@
   ],
   "Accessibility": {
     "violations": [
+      {
+        "id": "frame-title",
+        "impact": "serious",
+        "tags": [
+          "cat.text-alternatives",
+          "wcag2a",
+          "wcag241",
+          "wcag412",
+          "section508",
+          "section508.22.i"
+        ],
+        "nodes": [
+          {
+            "target": [
+              "iframe"
+            ],
+            "failureSummary": "Fix any of the following:\n  Element has no title attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
+            "node": {
+              "lhId": "6-41-IFRAME",
+              "devtoolsNodePath": "2,HTML,1,BODY,33,IFRAME",
+              "selector": "body > iframe",
+              "boundingRect": {
+                "top": 1167,
+                "bottom": 1321,
+                "left": 8,
+                "right": 312,
+                "width": 304,
+                "height": 154
+              },
+              "snippet": "<iframe tabindex=\"-1\" src=\"focusable-iframe.html\">",
+              "nodeLabel": "body > iframe"
+            },
+            "relatedNodes": []
+          }
+        ]
+      },
       {
         "id": "html-has-lang",
         "impact": "serious",
@@ -11703,16 +11770,16 @@
             ],
             "failureSummary": "Fix any of the following:\n  The <html> element does not have a lang attribute",
             "node": {
-              "lhId": "5-48-HTML",
-              "devtoolsNodePath": "3,HTML",
+              "lhId": "6-49-HTML",
+              "devtoolsNodePath": "2,HTML",
               "selector": "html",
               "boundingRect": {
                 "top": 0,
-                "bottom": 1365,
+                "bottom": 1535,
                 "left": 0,
                 "right": 360,
                 "width": 360,
-                "height": 1365
+                "height": 1535
               },
               "snippet": "<html>",
               "nodeLabel": "html"
@@ -11739,8 +11806,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-49-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,14,IMG",
+              "lhId": "6-50-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,14,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 639,
@@ -11761,8 +11828,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-50-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,17,IMG",
+              "lhId": "6-51-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,17,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -11783,8 +11850,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-51-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,19,IMG",
+              "lhId": "6-52-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,19,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -11805,8 +11872,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-52-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,21,IMG",
+              "lhId": "6-53-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,21,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -11827,8 +11894,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-53-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,23,IMG",
+              "lhId": "6-54-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,23,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -11849,8 +11916,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-54-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,25,IMG",
+              "lhId": "6-55-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,25,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -11871,8 +11938,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-55-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,27,IMG",
+              "lhId": "6-56-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,27,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 658,
@@ -11889,44 +11956,44 @@
           },
           {
             "target": [
-              "img:nth-child(39)"
+              "img:nth-child(41)"
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-56-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,66,IMG",
+              "lhId": "6-57-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,70,IMG",
               "selector": "body > img",
               "boundingRect": {
-                "top": 1295,
-                "bottom": 1311,
-                "left": 322,
-                "right": 338,
+                "top": 1464,
+                "bottom": 1480,
+                "left": 310,
+                "right": 326,
                 "width": 16,
                 "height": 16
               },
-              "snippet": "<img src=\"blob:http://localhost:10200/84c78bd5-a720-43b4-93e0-26591a9ff8ee\">",
+              "snippet": "<img src=\"blob:http://localhost:10200/6692e848-7cb2-40b2-8f33-f794eec50d08\">",
               "nodeLabel": "body > img"
             },
             "relatedNodes": []
           },
           {
             "target": [
-              "img:nth-child(47)"
+              "img:nth-child(49)"
             ],
             "failureSummary": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-57-IMG",
-              "devtoolsNodePath": "3,HTML,1,BODY,78,IMG",
+              "lhId": "6-58-IMG",
+              "devtoolsNodePath": "2,HTML,1,BODY,82,IMG",
               "selector": "body > img",
               "boundingRect": {
-                "top": 1337,
-                "bottom": 1353,
+                "top": 1507,
+                "bottom": 1523,
                 "left": 8,
                 "right": 24,
                 "width": 16,
                 "height": 16
               },
-              "snippet": "<img src=\"filesystem:http://localhost:10200/temporary/empty-0.48387978403091236.png\">",
+              "snippet": "<img src=\"filesystem:http://localhost:10200/temporary/empty-0.5322789385846411.png\">",
               "nodeLabel": "body > img"
             },
             "relatedNodes": []
@@ -11952,16 +12019,16 @@
             ],
             "failureSummary": "Fix any of the following:\n  Form element does not have an implicit (wrapped) <label>\n  Form element does not have an explicit <label>\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element has no placeholder attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-41-INPUT",
-              "devtoolsNodePath": "3,HTML,1,BODY,61,INPUT",
+              "lhId": "6-42-INPUT",
+              "devtoolsNodePath": "2,HTML,1,BODY,65,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1274,
-                "bottom": 1295,
+                "top": 1442,
+                "bottom": 1464,
                 "left": 192,
-                "right": 345,
-                "width": 153,
-                "height": 21
+                "right": 339,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\" onpaste=\"event.preventDefault();\">",
               "nodeLabel": "body > input"
@@ -11970,20 +12037,20 @@
           },
           {
             "target": [
-              "input:nth-child(37)"
+              "input:nth-child(39)"
             ],
             "failureSummary": "Fix any of the following:\n  Form element does not have an implicit (wrapped) <label>\n  Form element does not have an explicit <label>\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element has no placeholder attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-42-INPUT",
-              "devtoolsNodePath": "3,HTML,1,BODY,63,INPUT",
+              "lhId": "6-43-INPUT",
+              "devtoolsNodePath": "2,HTML,1,BODY,67,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1296,
-                "bottom": 1317,
+                "top": 1465,
+                "bottom": 1486,
                 "left": 8,
-                "right": 161,
-                "width": 153,
-                "height": 21
+                "right": 155,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\">",
               "nodeLabel": "body > input"
@@ -11996,16 +12063,16 @@
             ],
             "failureSummary": "Fix any of the following:\n  Form element does not have an implicit (wrapped) <label>\n  Form element does not have an explicit <label>\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element has no placeholder attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-43-INPUT",
-              "devtoolsNodePath": "3,HTML,1,BODY,65,INPUT",
+              "lhId": "6-44-INPUT",
+              "devtoolsNodePath": "2,HTML,1,BODY,69,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1296,
-                "bottom": 1317,
-                "left": 165,
-                "right": 318,
-                "width": 153,
-                "height": 21
+                "top": 1465,
+                "bottom": 1486,
+                "left": 159,
+                "right": 306,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\" onpaste=\"return false;\">",
               "nodeLabel": "body > input"
@@ -12033,16 +12100,16 @@
             ],
             "failureSummary": "Fix all of the following:\n  Element is in tab order and does not have accessible text\n\nFix any of the following:\n  Element does not have text that is visible to screen readers\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute",
             "node": {
-              "lhId": "5-9-A",
-              "devtoolsNodePath": "3,HTML,1,BODY,57,A",
+              "lhId": "6-9-A",
+              "devtoolsNodePath": "2,HTML,1,BODY,61,A",
               "selector": "body > a",
               "boundingRect": {
-                "top": 1275,
-                "bottom": 1293,
+                "top": 1443,
+                "bottom": 1461,
                 "left": 192,
                 "right": 192,
                 "width": 0,
-                "height": 18
+                "height": 19
               },
               "snippet": "<a href=\"javascript:void(0)\" target=\"_blank\">",
               "nodeLabel": "body > a"
@@ -12055,16 +12122,16 @@
             ],
             "failureSummary": "Fix all of the following:\n  Element is in tab order and does not have accessible text\n\nFix any of the following:\n  Element does not have text that is visible to screen readers\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute",
             "node": {
-              "lhId": "5-10-A",
-              "devtoolsNodePath": "3,HTML,1,BODY,59,A",
+              "lhId": "6-10-A",
+              "devtoolsNodePath": "2,HTML,1,BODY,63,A",
               "selector": "body > a",
               "boundingRect": {
-                "top": 1275,
-                "bottom": 1293,
+                "top": 1443,
+                "bottom": 1461,
                 "left": 192,
                 "right": 192,
                 "width": 0,
-                "height": 18
+                "height": 19
               },
               "snippet": "<a href=\"mailto:inbox@email.com\" target=\"_blank\">",
               "nodeLabel": "body > a"
@@ -12090,8 +12157,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-58-OBJECT",
-              "devtoolsNodePath": "3,HTML,1,BODY,4,OBJECT",
+              "lhId": "6-59-OBJECT",
+              "devtoolsNodePath": "2,HTML,1,BODY,4,OBJECT",
               "selector": "body > object#5934a",
               "boundingRect": {
                 "top": 8,
@@ -12112,8 +12179,8 @@
             ],
             "failureSummary": "Fix any of the following:\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\"",
             "node": {
-              "lhId": "5-59-OBJECT",
-              "devtoolsNodePath": "3,HTML,1,BODY,5,OBJECT",
+              "lhId": "6-60-OBJECT",
+              "devtoolsNodePath": "2,HTML,1,BODY,5,OBJECT",
               "selector": "body > object#5934b",
               "boundingRect": {
                 "top": 162,
@@ -12131,7 +12198,40 @@
         ]
       }
     ],
-    "incomplete": [],
+    "incomplete": [
+      {
+        "id": "empty-table-header",
+        "impact": "minor",
+        "tags": [
+          "wcag131",
+          "cat.aria"
+        ],
+        "nodes": [
+          {
+            "target": [
+              "th"
+            ],
+            "failureSummary": "Fix any of the following:\n  Element does not have text that is visible to screen readers",
+            "node": {
+              "lhId": "6-45-TH",
+              "devtoolsNodePath": "2,HTML,1,BODY,35,TABLE,0,TBODY,0,TR,0,TH",
+              "selector": "table > tbody > tr > th",
+              "boundingRect": {
+                "top": 1327,
+                "bottom": 1329,
+                "left": 10,
+                "right": 12,
+                "width": 2,
+                "height": 2
+              },
+              "snippet": "<th>",
+              "nodeLabel": "table > tbody > tr > th"
+            },
+            "relatedNodes": []
+          }
+        ]
+      }
+    ],
     "notApplicable": [
       {
         "id": "accesskeys"
@@ -12179,7 +12279,7 @@
         "id": "duplicate-id-active"
       },
       {
-        "id": "frame-title"
+        "id": "frame-focusable-content"
       },
       {
         "id": "html-lang-valid"
@@ -12208,15 +12308,6 @@
       {
         "id": "select-name"
       },
-      {
-        "id": "tabindex"
-      },
-      {
-        "id": "td-headers-attr"
-      },
-      {
-        "id": "th-has-data-cells"
-      },
       {
         "id": "valid-lang"
       },
@@ -12224,7 +12315,7 @@
         "id": "video-caption"
       }
     ],
-    "version": "4.2.3"
+    "version": "4.3.5"
   },
   "TraceElements": [
     {
diff --git a/lighthouse-core/test/results/sample_v2.json b/lighthouse-core/test/results/sample_v2.json
index 17bb54286024..fe58af6c210c 100644
--- a/lighthouse-core/test/results/sample_v2.json
+++ b/lighthouse-core/test/results/sample_v2.json
@@ -11,7 +11,7 @@
     "hostUserAgent": "Mozilla/5.0 (Macintosh; Intel Mac OS X 10_15_7) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/95.0.4635.0 Safari/537.36",
     "benchmarkIndex": 1549,
     "credits": {
-      "axe-core": "4.2.3"
+      "axe-core": "4.3.5"
     }
   },
   "audits": {
@@ -3226,43 +3226,8 @@
       "title": "Script Treemap Data",
       "description": "Used for treemap app",
       "score": null,
-      "scoreDisplayMode": "informative",
-      "details": {
-        "type": "treemap-data",
-        "nodes": [
-          {
-            "name": "http://localhost:10200/dobetterweb/dbw_tester.html",
-            "resourceBytes": 7197
-          },
-          {
-            "name": "http://localhost:10200/dobetterweb/dbw_tester.js",
-            "resourceBytes": 824,
-            "unusedBytes": 0
-          },
-          {
-            "name": "http://localhost:10200/dobetterweb/empty_module.js?delay=500",
-            "resourceBytes": 60
-          },
-          {
-            "name": "http://localhost:10200/dobetterweb/fake-script-wp-includes",
-            "resourceBytes": 58
-          },
-          {
-            "name": "http://localhost:10200/dobetterweb/fcp-delayer.js?delay=5000",
-            "resourceBytes": 60
-          },
-          {
-            "name": "http://localhost:10200/dobetterweb/third_party/aggressive-promise-polyfill.js",
-            "resourceBytes": 166320,
-            "unusedBytes": 43507
-          },
-          {
-            "name": "http://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js",
-            "resourceBytes": 84245,
-            "unusedBytes": 59810
-          }
-        ]
-      }
+      "scoreDisplayMode": "error",
+      "errorMessage": "scriptCoverage.functions is not iterable"
     },
     "pwa-cross-browser": {
       "id": "pwa-cross-browser",
@@ -3515,6 +3480,56 @@
         "items": []
       }
     },
+    "empty-table-header": {
+      "id": "empty-table-header",
+      "title": "`table` headers have visible text",
+      "description": "`table` headers should have visible text so assistive technologies like screen readers may describe table contents appropriately. [Learn more](https://dequeuniversity.com/rules/axe/4.2/empty-table-header).",
+      "score": null,
+      "scoreDisplayMode": "informative",
+      "details": {
+        "type": "table",
+        "headings": [
+          {
+            "key": "node",
+            "itemType": "node",
+            "subItemsHeading": {
+              "key": "relatedNode",
+              "itemType": "node"
+            },
+            "text": "Failing Elements"
+          }
+        ],
+        "items": [
+          {
+            "node": {
+              "type": "node",
+              "lhId": "6-45-TH",
+              "path": "2,HTML,1,BODY,35,TABLE,0,TBODY,0,TR,0,TH",
+              "selector": "table > tbody > tr > th",
+              "boundingRect": {
+                "top": 1327,
+                "bottom": 1329,
+                "left": 10,
+                "right": 12,
+                "width": 2,
+                "height": 2
+              },
+              "snippet": "<th>",
+              "nodeLabel": "table > tbody > tr > th",
+              "explanation": "Fix any of the following:\n  Element does not have text that is visible to screen readers"
+            }
+          }
+        ],
+        "debugData": {
+          "type": "debugdata",
+          "impact": "minor",
+          "tags": [
+            "wcag131",
+            "cat.aria"
+          ]
+        }
+      }
+    },
     "form-field-multiple-labels": {
       "id": "form-field-multiple-labels",
       "title": "No form fields have multiple labels",
@@ -3522,12 +3537,66 @@
       "score": null,
       "scoreDisplayMode": "notApplicable"
     },
+    "frame-focusable-content": {
+      "id": "frame-focusable-content",
+      "title": "`<iframe>` elements with focusable content do not have a negative `tabindex`",
+      "description": "Focusable elements within an `<iframe>` element with a negative `tabindex` cannot be reached via keyboard navigation. [Learn more](https://dequeuniversity.com/rules/axe/4.2/frame-focusable-content).",
+      "score": null,
+      "scoreDisplayMode": "notApplicable"
+    },
     "frame-title": {
       "id": "frame-title",
-      "title": "`<frame>` or `<iframe>` elements have a title",
+      "title": "`<frame>` or `<iframe>` elements do not have a title",
       "description": "Screen reader users rely on frame titles to describe the contents of frames. [Learn more](https://web.dev/frame-title/).",
-      "score": null,
-      "scoreDisplayMode": "notApplicable"
+      "score": 0,
+      "scoreDisplayMode": "binary",
+      "details": {
+        "type": "table",
+        "headings": [
+          {
+            "key": "node",
+            "itemType": "node",
+            "subItemsHeading": {
+              "key": "relatedNode",
+              "itemType": "node"
+            },
+            "text": "Failing Elements"
+          }
+        ],
+        "items": [
+          {
+            "node": {
+              "type": "node",
+              "lhId": "6-41-IFRAME",
+              "path": "2,HTML,1,BODY,33,IFRAME",
+              "selector": "body > iframe",
+              "boundingRect": {
+                "top": 1167,
+                "bottom": 1321,
+                "left": 8,
+                "right": 312,
+                "width": 304,
+                "height": 154
+              },
+              "snippet": "<iframe tabindex=\"-1\" src=\"focusable-iframe.html\">",
+              "nodeLabel": "body > iframe",
+              "explanation": "Fix any of the following:\n  Element has no title attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\""
+            }
+          }
+        ],
+        "debugData": {
+          "type": "debugdata",
+          "impact": "serious",
+          "tags": [
+            "cat.text-alternatives",
+            "wcag2a",
+            "wcag241",
+            "wcag412",
+            "section508",
+            "section508.22.i"
+          ]
+        }
+      }
     },
     "heading-order": {
       "id": "heading-order",
@@ -3564,16 +3633,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-48-HTML",
-              "path": "3,HTML",
+              "lhId": "6-49-HTML",
+              "path": "2,HTML",
               "selector": "html",
               "boundingRect": {
                 "top": 0,
-                "bottom": 1365,
+                "bottom": 1535,
                 "left": 0,
                 "right": 360,
                 "width": 360,
-                "height": 1365
+                "height": 1535
               },
               "snippet": "<html>",
               "nodeLabel": "html",
@@ -3623,8 +3692,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-49-IMG",
-              "path": "3,HTML,1,BODY,14,IMG",
+              "lhId": "6-50-IMG",
+              "path": "2,HTML,1,BODY,14,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 639,
@@ -3642,8 +3711,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-50-IMG",
-              "path": "3,HTML,1,BODY,17,IMG",
+              "lhId": "6-51-IMG",
+              "path": "2,HTML,1,BODY,17,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -3661,8 +3730,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-51-IMG",
-              "path": "3,HTML,1,BODY,19,IMG",
+              "lhId": "6-52-IMG",
+              "path": "2,HTML,1,BODY,19,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -3680,8 +3749,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-52-IMG",
-              "path": "3,HTML,1,BODY,21,IMG",
+              "lhId": "6-53-IMG",
+              "path": "2,HTML,1,BODY,21,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -3699,8 +3768,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-53-IMG",
-              "path": "3,HTML,1,BODY,23,IMG",
+              "lhId": "6-54-IMG",
+              "path": "2,HTML,1,BODY,23,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -3718,8 +3787,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-54-IMG",
-              "path": "3,HTML,1,BODY,25,IMG",
+              "lhId": "6-55-IMG",
+              "path": "2,HTML,1,BODY,25,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 574,
@@ -3737,8 +3806,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-55-IMG",
-              "path": "3,HTML,1,BODY,27,IMG",
+              "lhId": "6-56-IMG",
+              "path": "2,HTML,1,BODY,27,IMG",
               "selector": "body > img",
               "boundingRect": {
                 "top": 658,
@@ -3756,18 +3825,18 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-56-IMG",
-              "path": "3,HTML,1,BODY,66,IMG",
+              "lhId": "6-57-IMG",
+              "path": "2,HTML,1,BODY,70,IMG",
               "selector": "body > img",
               "boundingRect": {
-                "top": 1295,
-                "bottom": 1311,
-                "left": 322,
-                "right": 338,
+                "top": 1464,
+                "bottom": 1480,
+                "left": 310,
+                "right": 326,
                 "width": 16,
                 "height": 16
               },
-              "snippet": "<img src=\"blob:http://localhost:10200/84c78bd5-a720-43b4-93e0-26591a9ff8ee\">",
+              "snippet": "<img src=\"blob:http://localhost:10200/6692e848-7cb2-40b2-8f33-f794eec50d08\">",
               "nodeLabel": "body > img",
               "explanation": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\""
             }
@@ -3775,18 +3844,18 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-57-IMG",
-              "path": "3,HTML,1,BODY,78,IMG",
+              "lhId": "6-58-IMG",
+              "path": "2,HTML,1,BODY,82,IMG",
               "selector": "body > img",
               "boundingRect": {
-                "top": 1337,
-                "bottom": 1353,
+                "top": 1507,
+                "bottom": 1523,
                 "left": 8,
                 "right": 24,
                 "width": 16,
                 "height": 16
               },
-              "snippet": "<img src=\"filesystem:http://localhost:10200/temporary/empty-0.48387978403091236.png\">",
+              "snippet": "<img src=\"filesystem:http://localhost:10200/temporary/empty-0.5322789385846411.png\">",
               "nodeLabel": "body > img",
               "explanation": "Fix any of the following:\n  Element does not have an alt attribute\n  aria-label attribute does not exist or is empty\n  aria-labelledby attribute does not exist, references elements that do not exist or references elements that are empty\n  Element has no title attribute\n  Element's default semantics were not overridden with role=\"none\" or role=\"presentation\""
             }
@@ -3836,16 +3905,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-41-INPUT",
-              "path": "3,HTML,1,BODY,61,INPUT",
+              "lhId": "6-42-INPUT",
+              "path": "2,HTML,1,BODY,65,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1274,
-                "bottom": 1295,
+                "top": 1442,
+                "bottom": 1464,
                 "left": 192,
-                "right": 345,
-                "width": 153,
-                "height": 21
+                "right": 339,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\" onpaste=\"event.preventDefault();\">",
               "nodeLabel": "body > input",
@@ -3855,16 +3924,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-42-INPUT",
-              "path": "3,HTML,1,BODY,63,INPUT",
+              "lhId": "6-43-INPUT",
+              "path": "2,HTML,1,BODY,67,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1296,
-                "bottom": 1317,
+                "top": 1465,
+                "bottom": 1486,
                 "left": 8,
-                "right": 161,
-                "width": 153,
-                "height": 21
+                "right": 155,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\">",
               "nodeLabel": "body > input",
@@ -3874,16 +3943,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-43-INPUT",
-              "path": "3,HTML,1,BODY,65,INPUT",
+              "lhId": "6-44-INPUT",
+              "path": "2,HTML,1,BODY,69,INPUT",
               "selector": "body > input",
               "boundingRect": {
-                "top": 1296,
-                "bottom": 1317,
-                "left": 165,
-                "right": 318,
-                "width": 153,
-                "height": 21
+                "top": 1465,
+                "bottom": 1486,
+                "left": 159,
+                "right": 306,
+                "width": 147,
+                "height": 22
               },
               "snippet": "<input type=\"password\" onpaste=\"return false;\">",
               "nodeLabel": "body > input",
@@ -3929,16 +3998,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-9-A",
-              "path": "3,HTML,1,BODY,57,A",
+              "lhId": "6-9-A",
+              "path": "2,HTML,1,BODY,61,A",
               "selector": "body > a",
               "boundingRect": {
-                "top": 1275,
-                "bottom": 1293,
+                "top": 1443,
+                "bottom": 1461,
                 "left": 192,
                 "right": 192,
                 "width": 0,
-                "height": 18
+                "height": 19
               },
               "snippet": "<a href=\"javascript:void(0)\" target=\"_blank\">",
               "nodeLabel": "body > a",
@@ -3948,16 +4017,16 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-10-A",
-              "path": "3,HTML,1,BODY,59,A",
+              "lhId": "6-10-A",
+              "path": "2,HTML,1,BODY,63,A",
               "selector": "body > a",
               "boundingRect": {
-                "top": 1275,
-                "bottom": 1293,
+                "top": 1443,
+                "bottom": 1461,
                 "left": 192,
                 "right": 192,
                 "width": 0,
-                "height": 18
+                "height": 19
               },
               "snippet": "<a href=\"mailto:inbox@email.com\" target=\"_blank\">",
               "nodeLabel": "body > a",
@@ -4036,8 +4105,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-58-OBJECT",
-              "path": "3,HTML,1,BODY,4,OBJECT",
+              "lhId": "6-59-OBJECT",
+              "path": "2,HTML,1,BODY,4,OBJECT",
               "selector": "body > object#5934a",
               "boundingRect": {
                 "top": 8,
@@ -4055,8 +4124,8 @@
           {
             "node": {
               "type": "node",
-              "lhId": "5-59-OBJECT",
-              "path": "3,HTML,1,BODY,5,OBJECT",
+              "lhId": "6-60-OBJECT",
+              "path": "2,HTML,1,BODY,5,OBJECT",
               "selector": "body > object#5934b",
               "boundingRect": {
                 "top": 162,
@@ -4089,22 +4158,37 @@
       "id": "tabindex",
       "title": "No element has a `[tabindex]` value greater than 0",
       "description": "A value greater than 0 implies an explicit navigation ordering. Although technically valid, this often creates frustrating experiences for users who rely on assistive technologies. [Learn more](https://web.dev/tabindex/).",
-      "score": null,
-      "scoreDisplayMode": "notApplicable"
+      "score": 1,
+      "scoreDisplayMode": "binary",
+      "details": {
+        "type": "table",
+        "headings": [],
+        "items": []
+      }
     },
     "td-headers-attr": {
       "id": "td-headers-attr",
       "title": "Cells in a `<table>` element that use the `[headers]` attribute refer to table cells within the same table.",
       "description": "Screen readers have features to make navigating tables easier. Ensuring `<td>` cells using the `[headers]` attribute only refer to other cells in the same table may improve the experience for screen reader users. [Learn more](https://web.dev/td-headers-attr/).",
-      "score": null,
-      "scoreDisplayMode": "notApplicable"
+      "score": 1,
+      "scoreDisplayMode": "binary",
+      "details": {
+        "type": "table",
+        "headings": [],
+        "items": []
+      }
     },
     "th-has-data-cells": {
       "id": "th-has-data-cells",
       "title": "`<th>` elements and elements with `[role=\"columnheader\"/\"rowheader\"]` have data cells they describe.",
       "description": "Screen readers have features to make navigating tables easier. Ensuring table headers always refer to some set of cells may improve the experience for screen reader users. [Learn more](https://web.dev/th-has-data-cells/).",
-      "score": null,
-      "scoreDisplayMode": "notApplicable"
+      "score": 1,
+      "scoreDisplayMode": "binary",
+      "details": {
+        "type": "table",
+        "headings": [],
+        "items": []
+      }
     },
     "valid-lang": {
       "id": "valid-lang",
@@ -4581,57 +4665,9 @@
       "id": "unused-javascript",
       "title": "Reduce unused JavaScript",
       "description": "Reduce unused JavaScript and defer loading scripts until they are required to decrease bytes consumed by network activity. [Learn more](https://web.dev/unused-javascript/).",
-      "score": 0.58,
-      "scoreDisplayMode": "numeric",
-      "numericValue": 600,
-      "numericUnit": "millisecond",
-      "displayValue": "Potential savings of 64 KiB",
-      "details": {
-        "type": "opportunity",
-        "headings": [
-          {
-            "key": "url",
-            "valueType": "url",
-            "subItemsHeading": {
-              "key": "source",
-              "valueType": "code"
-            },
-            "label": "URL"
-          },
-          {
-            "key": "totalBytes",
-            "valueType": "bytes",
-            "subItemsHeading": {
-              "key": "sourceBytes"
-            },
-            "label": "Transfer Size"
-          },
-          {
-            "key": "wastedBytes",
-            "valueType": "bytes",
-            "subItemsHeading": {
-              "key": "sourceWastedBytes"
-            },
-            "label": "Potential Savings"
-          }
-        ],
-        "items": [
-          {
-            "url": "http://localhost:10200/dobetterweb/third_party/aggressive-promise-polyfill.js",
-            "totalBytes": 166550,
-            "wastedBytes": 43567,
-            "wastedPercent": 26.158609908609908
-          },
-          {
-            "url": "http://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js",
-            "totalBytes": 30346,
-            "wastedBytes": 21544,
-            "wastedPercent": 70.99531129443884
-          }
-        ],
-        "overallSavingsMs": 600,
-        "overallSavingsBytes": 65111
-      }
+      "score": null,
+      "scoreDisplayMode": "error",
+      "errorMessage": "scriptCoverage.functions is not iterable"
     },
     "modern-image-formats": {
       "id": "modern-image-formats",
@@ -6357,14 +6393,24 @@
           "weight": 10,
           "group": "a11y-aria"
         },
+        {
+          "id": "empty-table-header",
+          "weight": 0,
+          "group": "a11y-tables-lists"
+        },
         {
           "id": "form-field-multiple-labels",
           "weight": 0,
           "group": "a11y-names-labels"
         },
         {
-          "id": "frame-title",
+          "id": "frame-focusable-content",
           "weight": 0,
+          "group": "a11y-navigation"
+        },
+        {
+          "id": "frame-title",
+          "weight": 3,
           "group": "a11y-names-labels"
         },
         {
@@ -6429,17 +6475,17 @@
         },
         {
           "id": "tabindex",
-          "weight": 0,
+          "weight": 3,
           "group": "a11y-navigation"
         },
         {
           "id": "td-headers-attr",
-          "weight": 0,
+          "weight": 3,
           "group": "a11y-tables-lists"
         },
         {
           "id": "th-has-data-cells",
-          "weight": 0,
+          "weight": 3,
           "group": "a11y-tables-lists"
         },
         {
@@ -6494,7 +6540,7 @@
         }
       ],
       "id": "accessibility",
-      "score": 0.78
+      "score": 0.77
     },
     "best-practices": {
       "title": "Best Practices",
@@ -7417,18 +7463,6 @@
         "duration": 100,
         "entryType": "measure"
       },
-      {
-        "startTime": 0,
-        "name": "lh:computed:UnusedJavascriptSummary",
-        "duration": 100,
-        "entryType": "measure"
-      },
-      {
-        "startTime": 0,
-        "name": "lh:computed:UnusedJavascriptSummary",
-        "duration": 100,
-        "entryType": "measure"
-      },
       {
         "startTime": 0,
         "name": "lh:audit:pwa-cross-browser",
@@ -7597,12 +7631,24 @@
         "duration": 100,
         "entryType": "measure"
       },
+      {
+        "startTime": 0,
+        "name": "lh:audit:empty-table-header",
+        "duration": 100,
+        "entryType": "measure"
+      },
       {
         "startTime": 0,
         "name": "lh:audit:form-field-multiple-labels",
         "duration": 100,
         "entryType": "measure"
       },
+      {
+        "startTime": 0,
+        "name": "lh:audit:frame-focusable-content",
+        "duration": 100,
+        "entryType": "measure"
+      },
       {
         "startTime": 0,
         "name": "lh:audit:frame-title",
@@ -8301,7 +8347,6 @@
         "audits[total-byte-weight].details.headings[0].text",
         "audits[render-blocking-resources].details.headings[0].label",
         "audits[unminified-javascript].details.headings[0].label",
-        "audits[unused-javascript].details.headings[0].label",
         "audits[modern-image-formats].details.headings[1].label",
         "audits[uses-text-compression].details.headings[0].label",
         "audits[uses-responsive-images].details.headings[1].label",
@@ -8544,7 +8589,6 @@
         "audits[total-byte-weight].details.headings[1].text",
         "audits[render-blocking-resources].details.headings[1].label",
         "audits[unminified-javascript].details.headings[1].label",
-        "audits[unused-javascript].details.headings[1].label",
         "audits[uses-text-compression].details.headings[1].label"
       ],
       "lighthouse-core/lib/i18n/i18n.js | columnOverBudget": [
@@ -8954,13 +8998,35 @@
       "lighthouse-core/audits/accessibility/duplicate-id-aria.js | description": [
         "audits[duplicate-id-aria].description"
       ],
+      "lighthouse-core/audits/accessibility/empty-table-header.js | title": [
+        "audits[empty-table-header].title"
+      ],
+      "lighthouse-core/audits/accessibility/empty-table-header.js | description": [
+        "audits[empty-table-header].description"
+      ],
+      "lighthouse-core/lib/i18n/i18n.js | columnFailingElem": [
+        "audits[empty-table-header].details.headings[0].text",
+        "audits[frame-title].details.headings[0].text",
+        "audits[html-has-lang].details.headings[0].text",
+        "audits[image-alt].details.headings[0].text",
+        "audits.label.details.headings[0].text",
+        "audits[link-name].details.headings[0].text",
+        "audits[object-alt].details.headings[0].text",
+        "audits[password-inputs-can-be-pasted-into].details.headings[0].text"
+      ],
       "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | title": [
         "audits[form-field-multiple-labels].title"
       ],
       "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | description": [
         "audits[form-field-multiple-labels].description"
       ],
-      "lighthouse-core/audits/accessibility/frame-title.js | title": [
+      "lighthouse-core/audits/accessibility/frame-focusable-content.js | title": [
+        "audits[frame-focusable-content].title"
+      ],
+      "lighthouse-core/audits/accessibility/frame-focusable-content.js | description": [
+        "audits[frame-focusable-content].description"
+      ],
+      "lighthouse-core/audits/accessibility/frame-title.js | failureTitle": [
         "audits[frame-title].title"
       ],
       "lighthouse-core/audits/accessibility/frame-title.js | description": [
@@ -8978,14 +9044,6 @@
       "lighthouse-core/audits/accessibility/html-has-lang.js | description": [
         "audits[html-has-lang].description"
       ],
-      "lighthouse-core/lib/i18n/i18n.js | columnFailingElem": [
-        "audits[html-has-lang].details.headings[0].text",
-        "audits[image-alt].details.headings[0].text",
-        "audits.label.details.headings[0].text",
-        "audits[link-name].details.headings[0].text",
-        "audits[object-alt].details.headings[0].text",
-        "audits[password-inputs-can-be-pasted-into].details.headings[0].text"
-      ],
       "lighthouse-core/audits/accessibility/html-lang-valid.js | title": [
         "audits[html-lang-valid].title"
       ],
@@ -9130,7 +9188,6 @@
       "lighthouse-core/lib/i18n/i18n.js | columnWastedBytes": [
         "audits[render-blocking-resources].details.headings[2].label",
         "audits[unminified-javascript].details.headings[2].label",
-        "audits[unused-javascript].details.headings[2].label",
         "audits[modern-image-formats].details.headings[3].label",
         "audits[uses-text-compression].details.headings[2].label",
         "audits[uses-responsive-images].details.headings[3].label",
@@ -9156,12 +9213,6 @@
           },
           "path": "audits[unminified-javascript].displayValue"
         },
-        {
-          "values": {
-            "wastedBytes": 65111
-          },
-          "path": "audits[unused-javascript].displayValue"
-        },
         {
           "values": {
             "wastedBytes": 77874.3
diff --git a/report/test/renderer/report-renderer-axe-test.js b/report/test/renderer/report-renderer-axe-test.js
index 34a4ef0579bc..468c91cb794d 100644
--- a/report/test/renderer/report-renderer-axe-test.js
+++ b/report/test/renderer/report-renderer-axe-test.js
@@ -46,6 +46,8 @@ describe('ReportRendererAxe', () => {
           'heading-order': {enabled: true},
           'meta-viewport': {enabled: true},
           'aria-treeitem-name': {enabled: true},
+          // May not be a real issue. https://github.com/dequelabs/axe-core/issues/2958
+          'nested-interactive': {enabled: false},
         },
       };
 
diff --git a/shared/localization/locales/en-US.json b/shared/localization/locales/en-US.json
index 84515bb31a1a..87fcd0549cd1 100644
--- a/shared/localization/locales/en-US.json
+++ b/shared/localization/locales/en-US.json
@@ -359,6 +359,15 @@
   "lighthouse-core/audits/accessibility/duplicate-id-aria.js | title": {
     "message": "ARIA IDs are unique"
   },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | description": {
+    "message": "`table` headers should have visible text so assistive technologies like screen readers may describe table contents appropriately. [Learn more](https://dequeuniversity.com/rules/axe/4.2/empty-table-header)."
+  },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | failureTitle": {
+    "message": "`table` headers do not have visible text"
+  },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | title": {
+    "message": "`table` headers have visible text"
+  },
   "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | description": {
     "message": "Form fields with multiple labels can be confusingly announced by assistive technologies like screen readers which use either the first, the last, or all of the labels. [Learn more](https://web.dev/form-field-multiple-labels/)."
   },
@@ -368,6 +377,15 @@
   "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | title": {
     "message": "No form fields have multiple labels"
   },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | description": {
+    "message": "Focusable elements within an `<iframe>` element with a negative `tabindex` cannot be reached via keyboard navigation. [Learn more](https://dequeuniversity.com/rules/axe/4.2/frame-focusable-content)."
+  },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | failureTitle": {
+    "message": "`<iframe>` elements with focusable content have a negative `tabindex`"
+  },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | title": {
+    "message": "`<iframe>` elements with focusable content do not have a negative `tabindex`"
+  },
   "lighthouse-core/audits/accessibility/frame-title.js | description": {
     "message": "Screen reader users rely on frame titles to describe the contents of frames. [Learn more](https://web.dev/frame-title/)."
   },
diff --git a/shared/localization/locales/en-XL.json b/shared/localization/locales/en-XL.json
index e02e12040df6..e35023c542b3 100644
--- a/shared/localization/locales/en-XL.json
+++ b/shared/localization/locales/en-XL.json
@@ -359,6 +359,15 @@
   "lighthouse-core/audits/accessibility/duplicate-id-aria.js | title": {
     "message": "ÂŔÎÁ ÎD́ŝ ár̂é ûńîq́ûé"
   },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | description": {
+    "message": "`table` ĥéâd́êŕŝ śĥóûĺd̂ h́âv́ê v́îśîb́l̂é t̂éx̂t́ ŝó âśŝíŝt́îv́ê t́êćĥńôĺôǵîéŝ ĺîḱê śĉŕêén̂ ŕêád̂ér̂ś m̂áŷ d́êśĉŕîb́ê t́âb́l̂é ĉón̂t́êńt̂ś âṕp̂ŕôṕr̂íât́êĺŷ. [Ĺêár̂ń m̂ór̂é](https://dequeuniversity.com/rules/axe/4.2/empty-table-header)."
+  },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | failureTitle": {
+    "message": "`table` ĥéâd́êŕŝ d́ô ńôt́ ĥáv̂é v̂íŝíb̂ĺê t́êx́t̂"
+  },
+  "lighthouse-core/audits/accessibility/empty-table-header.js | title": {
+    "message": "`table` ĥéâd́êŕŝ h́âv́ê v́îśîb́l̂é t̂éx̂t́"
+  },
   "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | description": {
     "message": "F̂ór̂ḿ f̂íêĺd̂ś ŵít̂h́ m̂úl̂t́îṕl̂é l̂áb̂él̂ś ĉán̂ b́ê ćôńf̂úŝín̂ǵl̂ý âńn̂óûńĉéd̂ b́ŷ áŝśîśt̂ív̂é t̂éĉh́n̂ól̂óĝíêś l̂ík̂é ŝćr̂éêń r̂éâd́êŕŝ ẃĥíĉh́ ûśê éît́ĥér̂ t́ĥé f̂ír̂śt̂, t́ĥé l̂áŝt́, ôŕ âĺl̂ óf̂ t́ĥé l̂áb̂él̂ś. [L̂éâŕn̂ ḿôŕê](https://web.dev/form-field-multiple-labels/)."
   },
@@ -368,6 +377,15 @@
   "lighthouse-core/audits/accessibility/form-field-multiple-labels.js | title": {
     "message": "N̂ó f̂ór̂ḿ f̂íêĺd̂ś ĥáv̂é m̂úl̂t́îṕl̂é l̂áb̂él̂ś"
   },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | description": {
+    "message": "F̂óĉúŝáb̂ĺê él̂ém̂én̂t́ŝ ẃît́ĥín̂ án̂ `<iframe>` él̂ém̂én̂t́ ŵít̂h́ â ńêǵât́îv́ê `tabindex` ćâńn̂ót̂ b́ê ŕêáĉh́êd́ v̂íâ ḱêýb̂óâŕd̂ ńâv́îǵât́îón̂. [Ĺêár̂ń m̂ór̂é](https://dequeuniversity.com/rules/axe/4.2/frame-focusable-content)."
+  },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | failureTitle": {
+    "message": "`<iframe>` êĺêḿêńt̂ś ŵít̂h́ f̂óĉúŝáb̂ĺê ćôńt̂én̂t́ ĥáv̂é â ńêǵât́îv́ê `tabindex`"
+  },
+  "lighthouse-core/audits/accessibility/frame-focusable-content.js | title": {
+    "message": "`<iframe>` êĺêḿêńt̂ś ŵít̂h́ f̂óĉúŝáb̂ĺê ćôńt̂én̂t́ d̂ó n̂ót̂ h́âv́ê á n̂éĝát̂ív̂é `tabindex`"
+  },
   "lighthouse-core/audits/accessibility/frame-title.js | description": {
     "message": "Ŝćr̂éêń r̂éâd́êŕ ûśêŕŝ ŕêĺŷ ón̂ f́r̂ám̂é t̂ít̂ĺêś t̂ó d̂éŝćr̂íb̂é t̂h́ê ćôńt̂én̂t́ŝ óf̂ f́r̂ám̂éŝ. [Ĺêár̂ń m̂ór̂é](https://web.dev/frame-title/)."
   },
diff --git a/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-export-run-expected.txt b/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-export-run-expected.txt
index 57304d5d24dc..733b1d4624a1 100644
--- a/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-export-run-expected.txt
+++ b/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-export-run-expected.txt
@@ -2,11 +2,11 @@ Tests that exporting works.
 
 ++++++++ testExportHtml
 
-# of .lh-audit divs (original): 136
+# of .lh-audit divs (original): 139
 
-# of .lh-audit divs (exported html): 136
+# of .lh-audit divs (exported html): 139
 
 ++++++++ testExportJson
 
-# of audits (json): 152
+# of audits (json): 156
 
diff --git a/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-successful-run-expected.txt b/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-successful-run-expected.txt
index d5a0882aa021..1b2e2e57f13e 100644
--- a/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-successful-run-expected.txt
+++ b/third-party/chromium-webtests/webtests/http/tests/devtools/lighthouse/lighthouse-successful-run-expected.txt
@@ -261,7 +261,9 @@ Auditing: Definition list items are wrapped in `<dl>` elements
 Auditing: Document has a `<title>` element
 Auditing: `[id]` attributes on active, focusable elements are unique
 Auditing: ARIA IDs are unique
+Auditing: `table` headers have visible text
 Auditing: No form fields have multiple labels
+Auditing: `<iframe>` elements with focusable content do not have a negative `tabindex`
 Auditing: `<frame>` or `<iframe>` elements have a title
 Auditing: Heading elements appear in a sequentially-descending order
 Auditing: `<html>` element has a `[lang]` attribute
@@ -434,6 +436,7 @@ duplicate-id-aria: notApplicable
 duplicate-tags: notApplicable
 duplicated-javascript: numeric
 efficient-animated-content: flaky
+empty-table-header: notApplicable
 errors-in-console: pass
 final-screenshot: ERROR Chrome didn't collect any screenshots during the page load. Please make sure there is content visible on the page, and then try re-running Lighthouse. (NO_SCREENSHOTS)
 first-ad-render: notApplicable
@@ -444,6 +447,7 @@ focusable-controls: manual
 font-display: pass
 font-size: fail
 form-field-multiple-labels: notApplicable
+frame-focusable-content: notApplicable
 frame-title: notApplicable
 full-page-screenshot: informative
 geolocation-on-start: pass
@@ -612,6 +616,7 @@ duplicate-id-aria
 duplicate-tags
 duplicated-javascript
 efficient-animated-content
+empty-table-header
 errors-in-console
 first-ad-render
 focus-traps
@@ -619,6 +624,7 @@ focusable-controls
 font-display
 font-size
 form-field-multiple-labels
+frame-focusable-content
 frame-title
 geolocation-on-start
 gpt-bids-parallel