diff --git a/DESCRIPTION b/DESCRIPTION
index f82aa808..27badc44 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -64,6 +64,7 @@ Collate:
     'error-checks.R'
     'font.R'
     'global-vars.R'
+    'helpers.R'
     'histogram-datamapping.R'
     'label.R'
     'messages.R'
diff --git a/NAMESPACE b/NAMESPACE
index 7d8ba79a..acf90922 100644
--- a/NAMESPACE
+++ b/NAMESPACE
@@ -112,7 +112,9 @@ export(getLnTickLabels)
 export(getLogTickLabels)
 export(getPKRatioMeasure)
 export(getPiTickLabels)
+export(getSameLimits)
 export(getSqrtTickLabels)
+export(getSymmetricLimits)
 export(initializePlot)
 export(loadThemeFromJson)
 export(plotBoxWhisker)
diff --git a/R/aaa-utilities.R b/R/aaa-utilities.R
index 187ea083..58b32081 100644
--- a/R/aaa-utilities.R
+++ b/R/aaa-utilities.R
@@ -92,6 +92,7 @@
 
 #' @title .updateAxes
 #' @description Updates the plot axes
+#' @param plotObject A `ggplot` object
 #' @return A `ggplot` object
 #' @keywords internal
 .updateAxes <- function(plotObject) {
@@ -100,3 +101,44 @@
   try(suppressMessages(plotObject <- setYAxis(plotObject)))
   return(plotObject)
 }
+
+#' @title .updateSameAxes
+#' @description Updates plot configuration axes to get same limits
+#' @param plotObject A `ggplot` object
+#' @param data A data.frame
+#' @param dataMapping A `DataMapping` object
+#' @return A `ggplot` object
+#' @keywords internal
+.updateSameAxes <- function(plotObject, data, dataMapping) {
+  if(!all(
+    plotObject$plotConfiguration$defaultSymmetricAxes,
+    isEmpty(plotObject$plotConfiguration$xAxis$limits),
+    isEmpty(plotObject$plotConfiguration$yAxis$limits)
+  )){
+    return(plotObject)
+  }
+  limits <- .getSameLimitsFromMapping(data, dataMapping)
+  plotObject$plotConfiguration$xAxis$limits <- limits
+  plotObject$plotConfiguration$yAxis$limits <- limits
+  return(plotObject)
+}
+
+#' @title .updateSymmetricAxes
+#' @description Updates plot configuration axes to get symmetric limits
+#' @param plotObject A `ggplot` object
+#' @param data A data.frame
+#' @param dataMapping A `DataMapping` object
+#' @return A `ggplot` object
+#' @keywords internal
+.updateSymmetricAxes <- function(plotObject, data, dataMapping) {
+  if(!all(
+    plotObject$plotConfiguration$defaultSymmetricAxes,
+    isEmpty(plotObject$plotConfiguration$yAxis$limits)
+  )){
+    return(plotObject)
+  }
+  limits <- getSymmetricLimits(data[, dataMapping$y])
+  plotObject$plotConfiguration$yAxis$limits <- limits
+  return(plotObject)
+}
+
diff --git a/R/helpers.R b/R/helpers.R
new file mode 100644
index 00000000..4310eba9
--- /dev/null
+++ b/R/helpers.R
@@ -0,0 +1,39 @@
+#' @title getSymmetricLimits
+#' @description Get symmetric limits from a set of values
+#' @param values numeric values
+#' @return An array of 2 symmetric values equally distant from 0
+#' @export
+#' @examples 
+#' getSymmetricLimits(seq(-3, 8))
+#' 
+getSymmetricLimits <- function(values){
+  validateIsNumeric(values, nullAllowed = TRUE)
+  # Remove Inf and NA values
+  values <- values[!is.infinite(values)]
+  values <- values[!is.na(values)]
+  if(isEmpty(values)){
+    return(NULL)
+  }
+  return(c(-max(abs(values)), max(abs(values))))
+}
+
+
+#' @title getSameLimits
+#' @description Get same limits from multiple sets of values
+#' @param ... numeric values
+#' @return An array of 2 values
+#' @export
+#' @examples 
+#' getSameLimits(seq(-3, 8), seq(-12, 4))
+#' 
+getSameLimits <- function(...){
+  values <- c(...)
+  validateIsNumeric(values, nullAllowed = TRUE)
+  # Remove Inf and NA values
+  values <- values[!is.infinite(values)]
+  values <- values[!is.na(values)]
+  if(isEmpty(values)){
+    return(NULL)
+  }
+  return(c(min(values), max(values)))
+}
\ No newline at end of file
diff --git a/R/plot-obs-vs-pred.R b/R/plot-obs-vs-pred.R
index e4329a52..3819edc1 100644
--- a/R/plot-obs-vs-pred.R
+++ b/R/plot-obs-vs-pred.R
@@ -137,6 +137,8 @@ plotObsVsPred <- function(data,
     data = mapData,
     mapLabels = mapLabels
   )
+  # Update axes limits if option symmetric and user did not define specific limits
+  plotObject <- .updateSameAxes(plotObject, mapData, dataMapping)
   plotObject <- .updateAxes(plotObject)
   return(plotObject)
 }
diff --git a/R/plot-res-vs-pred.R b/R/plot-res-vs-pred.R
index 2d285212..e01b897d 100644
--- a/R/plot-res-vs-pred.R
+++ b/R/plot-res-vs-pred.R
@@ -108,6 +108,7 @@ plotResVsPred <- function(data,
     data = mapData,
     mapLabels = mapLabels
   )
+  plotObject <- .updateSymmetricAxes(plotObject, mapData, dataMapping)
   plotObject <- .updateAxes(plotObject)
   return(plotObject)
 }
diff --git a/R/plotconfiguration.R b/R/plotconfiguration.R
index 6cb9f633..89cc36a1 100644
--- a/R/plotconfiguration.R
+++ b/R/plotconfiguration.R
@@ -4,6 +4,7 @@
 #' @field defaultXScale Default xAxis scale value when creating a `PlotConfiguration` object
 #' @field defaultYScale Default yAxis scale value when creating a `PlotConfiguration` object
 #' @field defaultExpand Default expand value when creating a `PlotConfiguration` object
+#' @field defaultSymmetricAxes Default option setting symmetric xAxis and/or yAxis limits when creating a `PlotConfiguration` object
 #' @family PlotConfiguration classes
 #' @references For examples, see:
 #' <https://www.open-systems-pharmacology.org/TLF-Library/articles/plot-configuration.html>
@@ -17,6 +18,7 @@ PlotConfiguration <- R6::R6Class(
     defaultXScale = "lin",
     defaultYScale = "lin",
     defaultExpand = FALSE,
+    defaultSymmetricAxes = FALSE,
 
     #' @description Create a new `PlotConfiguration` object
     #' @param title character or `Label` object defining plot title
@@ -317,19 +319,27 @@ DDIRatioPlotConfiguration <- R6::R6Class(
 
 #' @title ObsVsPredPlotConfiguration
 #' @description R6 class defining the configuration of a `ggplot` object for Obs vs Pred plots
+#' @field defaultSymmetricAxes Default option setting symmetric xAxis and/or yAxis limits when creating a `ObsVsPredPlotConfiguration` object
 #' @export
 #' @family PlotConfiguration classes
 ObsVsPredPlotConfiguration <- R6::R6Class(
   "ObsVsPredPlotConfiguration",
-  inherit = PlotConfiguration
+  inherit = PlotConfiguration,
+  public = list(
+    defaultSymmetricAxes = TRUE
+  )
 )
 
 #' @title ResVsPredPlotConfiguration
 #' @description R6 class defining the configuration of a `ggplot` object for Res vs Pred/Time plots
+#' @field defaultSymmetricAxes Default option setting symmetric xAxis and/or yAxis limits when creating a `ResVsPredPlotConfiguration` object
 #' @export
 ResVsPredPlotConfiguration <- R6::R6Class(
   "ResVsPredPlotConfiguration",
-  inherit = PlotConfiguration
+  inherit = PlotConfiguration,
+  public = list(
+    defaultSymmetricAxes = TRUE
+  )
 )
 
 #' @title ResVsTimePlotConfiguration
diff --git a/R/utilities-mapping.R b/R/utilities-mapping.R
index ae772a7f..7a1cad39 100644
--- a/R/utilities-mapping.R
+++ b/R/utilities-mapping.R
@@ -375,3 +375,14 @@ getLinesFromFoldDistance <- function(foldDistance) {
 
   return(aggregatedData)
 }
+
+
+#' @title .getSameLimitsFromMapping
+#' @description Get same axes limits from mapped data
+#' @param data A data.frame with labels mapped to properties and obtained from a `DataMapping` object
+#' @param dataMapping A `ObsVsPredDataMapping` object
+#' @keywords internal
+.getSameLimitsFromMapping <- function(data, dataMapping){
+  getSameLimits(data[,dataMapping$x], data[,dataMapping$y], data[,dataMapping$xmin], data[,dataMapping$xmax])
+}
+
diff --git a/man/ObsVsPredPlotConfiguration.Rd b/man/ObsVsPredPlotConfiguration.Rd
index f86aab69..51d5764b 100644
--- a/man/ObsVsPredPlotConfiguration.Rd
+++ b/man/ObsVsPredPlotConfiguration.Rd
@@ -20,6 +20,13 @@ Other PlotConfiguration classes:
 \section{Super class}{
 \code{tlf::PlotConfiguration} -> \code{ObsVsPredPlotConfiguration}
 }
+\section{Public fields}{
+\if{html}{\out{<div class="r6-fields">}}
+\describe{
+\item{\code{defaultSymmetricAxes}}{Default option setting symmetric xAxis and/or yAxis limits when creating a \code{ObsVsPredPlotConfiguration} object}
+}
+\if{html}{\out{</div>}}
+}
 \section{Methods}{
 \subsection{Public methods}{
 \itemize{
diff --git a/man/PlotConfiguration.Rd b/man/PlotConfiguration.Rd
index e1936917..04b6ef36 100644
--- a/man/PlotConfiguration.Rd
+++ b/man/PlotConfiguration.Rd
@@ -31,6 +31,8 @@ Other PlotConfiguration classes:
 \item{\code{defaultYScale}}{Default yAxis scale value when creating a \code{PlotConfiguration} object}
 
 \item{\code{defaultExpand}}{Default expand value when creating a \code{PlotConfiguration} object}
+
+\item{\code{defaultSymmetricAxes}}{Default option setting symmetric xAxis and/or yAxis limits when creating a \code{PlotConfiguration} object}
 }
 \if{html}{\out{</div>}}
 }
diff --git a/man/ResVsPredPlotConfiguration.Rd b/man/ResVsPredPlotConfiguration.Rd
index d04071ec..9edd31dc 100644
--- a/man/ResVsPredPlotConfiguration.Rd
+++ b/man/ResVsPredPlotConfiguration.Rd
@@ -9,6 +9,13 @@ R6 class defining the configuration of a \code{ggplot} object for Res vs Pred/Ti
 \section{Super class}{
 \code{tlf::PlotConfiguration} -> \code{ResVsPredPlotConfiguration}
 }
+\section{Public fields}{
+\if{html}{\out{<div class="r6-fields">}}
+\describe{
+\item{\code{defaultSymmetricAxes}}{Default option setting symmetric xAxis and/or yAxis limits when creating a \code{ResVsPredPlotConfiguration} object}
+}
+\if{html}{\out{</div>}}
+}
 \section{Methods}{
 \subsection{Public methods}{
 \itemize{
diff --git a/man/dot-getSameLimitsFromMapping.Rd b/man/dot-getSameLimitsFromMapping.Rd
new file mode 100644
index 00000000..f762970f
--- /dev/null
+++ b/man/dot-getSameLimitsFromMapping.Rd
@@ -0,0 +1,17 @@
+% Generated by roxygen2: do not edit by hand
+% Please edit documentation in R/utilities-mapping.R
+\name{.getSameLimitsFromMapping}
+\alias{.getSameLimitsFromMapping}
+\title{.getSameLimitsFromMapping}
+\usage{
+.getSameLimitsFromMapping(data, dataMapping)
+}
+\arguments{
+\item{data}{A data.frame with labels mapped to properties and obtained from a \code{DataMapping} object}
+
+\item{dataMapping}{A \code{ObsVsPredDataMapping} object}
+}
+\description{
+Get same axes limits from mapped data
+}
+\keyword{internal}
diff --git a/man/dot-updateAxes.Rd b/man/dot-updateAxes.Rd
index 9bc556a4..295af87b 100644
--- a/man/dot-updateAxes.Rd
+++ b/man/dot-updateAxes.Rd
@@ -6,6 +6,9 @@
 \usage{
 .updateAxes(plotObject)
 }
+\arguments{
+\item{plotObject}{A \code{ggplot} object}
+}
 \value{
 A \code{ggplot} object
 }
diff --git a/man/dot-updateSameAxes.Rd b/man/dot-updateSameAxes.Rd
new file mode 100644
index 00000000..bf29adb7
--- /dev/null
+++ b/man/dot-updateSameAxes.Rd
@@ -0,0 +1,22 @@
+% Generated by roxygen2: do not edit by hand
+% Please edit documentation in R/aaa-utilities.R
+\name{.updateSameAxes}
+\alias{.updateSameAxes}
+\title{.updateSameAxes}
+\usage{
+.updateSameAxes(plotObject, data, dataMapping)
+}
+\arguments{
+\item{plotObject}{A \code{ggplot} object}
+
+\item{data}{A data.frame}
+
+\item{dataMapping}{A \code{DataMapping} object}
+}
+\value{
+A \code{ggplot} object
+}
+\description{
+Updates plot configuration axes to get same limits
+}
+\keyword{internal}
diff --git a/man/dot-updateSymmetricAxes.Rd b/man/dot-updateSymmetricAxes.Rd
new file mode 100644
index 00000000..16e6a7f1
--- /dev/null
+++ b/man/dot-updateSymmetricAxes.Rd
@@ -0,0 +1,22 @@
+% Generated by roxygen2: do not edit by hand
+% Please edit documentation in R/aaa-utilities.R
+\name{.updateSymmetricAxes}
+\alias{.updateSymmetricAxes}
+\title{.updateSymmetricAxes}
+\usage{
+.updateSymmetricAxes(plotObject, data, dataMapping)
+}
+\arguments{
+\item{plotObject}{A \code{ggplot} object}
+
+\item{data}{A data.frame}
+
+\item{dataMapping}{A \code{DataMapping} object}
+}
+\value{
+A \code{ggplot} object
+}
+\description{
+Updates plot configuration axes to get symmetric limits
+}
+\keyword{internal}
diff --git a/man/getSameLimits.Rd b/man/getSameLimits.Rd
new file mode 100644
index 00000000..0c5ca9fb
--- /dev/null
+++ b/man/getSameLimits.Rd
@@ -0,0 +1,21 @@
+% Generated by roxygen2: do not edit by hand
+% Please edit documentation in R/helpers.R
+\name{getSameLimits}
+\alias{getSameLimits}
+\title{getSameLimits}
+\usage{
+getSameLimits(...)
+}
+\arguments{
+\item{...}{numeric values}
+}
+\value{
+An array of 2 values
+}
+\description{
+Get same limits from multiple sets of values
+}
+\examples{
+getSameLimits(seq(-3, 8), seq(-12, 4))
+
+}
diff --git a/man/getSymmetricLimits.Rd b/man/getSymmetricLimits.Rd
new file mode 100644
index 00000000..638bf758
--- /dev/null
+++ b/man/getSymmetricLimits.Rd
@@ -0,0 +1,21 @@
+% Generated by roxygen2: do not edit by hand
+% Please edit documentation in R/helpers.R
+\name{getSymmetricLimits}
+\alias{getSymmetricLimits}
+\title{getSymmetricLimits}
+\usage{
+getSymmetricLimits(values)
+}
+\arguments{
+\item{values}{numeric values}
+}
+\value{
+An array of 2 symmetric values equally distant from 0
+}
+\description{
+Get symmetric limits from a set of values
+}
+\examples{
+getSymmetricLimits(seq(-3, 8))
+
+}