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Reduce inefficiency in use of whole-genome alignments #14

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TBradley27 opened this issue Sep 13, 2020 · 0 comments
Open

Reduce inefficiency in use of whole-genome alignments #14

TBradley27 opened this issue Sep 13, 2020 · 0 comments

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@TBradley27
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At the moment, in order to generate multiple sequence alignments for each 3' UTR, FilTar downloads entire whole genome alignments and then extracts the relevant genomic co-ordinates (using the transcript co-ordinates of a reference species).

This is extremely inefficient and costly. FilTar should instead download MSAs on a UTR-by-UTR basis by more cleverly interacting with the UCSC server.

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