diff --git a/packages/angular_devkit/build_angular/src/babel/presets/application.ts b/packages/angular_devkit/build_angular/src/babel/presets/application.ts
index 366f07e48a10..13b184d6e37e 100644
--- a/packages/angular_devkit/build_angular/src/babel/presets/application.ts
+++ b/packages/angular_devkit/build_angular/src/babel/presets/application.ts
@@ -14,9 +14,26 @@ import type {
   makeLocalePlugin,
 } from '@angular/localize/tools';
 import { strict as assert } from 'assert';
+import browserslist from 'browserslist';
 import * as fs from 'fs';
 import * as path from 'path';
 
+/**
+ * List of browsers which are affected by a WebKit bug where class field
+ * initializers might have incorrect variable scopes.
+ *
+ * See: https://github.com/angular/angular-cli/issues/24355#issuecomment-1333477033
+ * See: https://github.com/WebKit/WebKit/commit/e8788a34b3d5f5b4edd7ff6450b80936bff396f2
+ */
+const safariClassFieldScopeBugBrowsers = new Set(
+  browserslist([
+    // Safari <15 is technically not supported via https://angular.io/guide/browser-support,
+    // but we apply the workaround if forcibly selected.
+    'Safari <=15',
+    'iOS <=15',
+  ]),
+);
+
 export type DiagnosticReporter = (type: 'error' | 'warning' | 'info', message: string) => void;
 
 /**
@@ -45,7 +62,6 @@ export interface ApplicationPresetOptions {
     linkerPluginCreator: typeof import('@angular/compiler-cli/linker/babel').createEs2015LinkerPlugin;
   };
 
-  forcePresetEnv?: boolean;
   forceAsyncTransformation?: boolean;
   instrumentCode?: {
     includedBasePath: string;
@@ -171,13 +187,26 @@ export default function (api: unknown, options: ApplicationPresetOptions) {
     );
   }
 
-  if (options.forcePresetEnv) {
+  // Applications code ES version can be controlled using TypeScript's `target` option.
+  // However, this doesn't effect libraries and hence we use preset-env to downlevel ES features
+  // based on the supported browsers in browserslist.
+  if (options.supportedBrowsers) {
+    const includePlugins: string[] = [];
+
+    // If a Safari browser affected by the class field scope bug is selected, we
+    // downlevel class properties by ensuring the class properties Babel plugin
+    // is always included- regardless of the preset-env targets.
+    if (options.supportedBrowsers.some((b) => safariClassFieldScopeBugBrowsers.has(b))) {
+      includePlugins.push('@babel/plugin-proposal-class-properties');
+    }
+
     presets.push([
       require('@babel/preset-env').default,
       {
         bugfixes: true,
         modules: false,
         targets: options.supportedBrowsers,
+        include: includePlugins,
         exclude: ['transform-typeof-symbol'],
       },
     ]);
diff --git a/packages/angular_devkit/build_angular/src/babel/webpack-loader.ts b/packages/angular_devkit/build_angular/src/babel/webpack-loader.ts
index 78af1b28d480..a43c01b03f3d 100644
--- a/packages/angular_devkit/build_angular/src/babel/webpack-loader.ts
+++ b/packages/angular_devkit/build_angular/src/babel/webpack-loader.ts
@@ -79,7 +79,6 @@ export default custom<ApplicationPresetOptions>(() => {
 
       const customOptions: ApplicationPresetOptions = {
         forceAsyncTransformation: false,
-        forcePresetEnv: false,
         angularLinker: undefined,
         i18n: undefined,
         instrumentCode: undefined,
@@ -105,14 +104,6 @@ export default custom<ApplicationPresetOptions>(() => {
         shouldProcess = true;
       }
 
-      // Analyze for ES target processing
-      if (customOptions.supportedBrowsers?.length) {
-        // Applications code ES version can be controlled using TypeScript's `target` option.
-        // However, this doesn't effect libraries and hence we use preset-env to downlevel ES fetaures
-        // based on the supported browsers in browserlist.
-        customOptions.forcePresetEnv = true;
-      }
-
       // Application code (TS files) will only contain native async if target is ES2017+.
       // However, third-party libraries can regardless of the target option.
       // APF packages with code in [f]esm2015 directories is downlevelled to ES2015 and
@@ -121,7 +112,9 @@ export default custom<ApplicationPresetOptions>(() => {
         !/[\\/][_f]?esm2015[\\/]/.test(this.resourcePath) && source.includes('async');
 
       shouldProcess ||=
-        customOptions.forceAsyncTransformation || customOptions.forcePresetEnv || false;
+        customOptions.forceAsyncTransformation ||
+        customOptions.supportedBrowsers !== undefined ||
+        false;
 
       // Analyze for i18n inlining
       if (
diff --git a/tests/legacy-cli/e2e/tests/misc/safari-15-class-properties.ts b/tests/legacy-cli/e2e/tests/misc/safari-15-class-properties.ts
new file mode 100644
index 000000000000..a0dce7186cff
--- /dev/null
+++ b/tests/legacy-cli/e2e/tests/misc/safari-15-class-properties.ts
@@ -0,0 +1,56 @@
+import { expectFileToExist, readFile, writeFile } from '../../utils/fs';
+import { ng } from '../../utils/process';
+import { updateJsonFile } from '../../utils/project';
+
+const unexpectedStaticFieldErrorMessage =
+  'Found unexpected static field. This indicates that the Safari <=v15 ' +
+  'workaround for a scope variable tracking is not working. ' +
+  'See: https://github.com/angular/angular-cli/pull/24357';
+
+export default async function () {
+  await updateJsonFile('angular.json', (workspace) => {
+    const build = workspace.projects['test-project'].architect.build;
+    build.defaultConfiguration = undefined;
+    build.options = {
+      ...build.options,
+      optimization: false,
+      outputHashing: 'none',
+    };
+  });
+
+  // Matches two types of static fields that indicate that the Safari bug
+  // may still occur. With the workaround this should not appear in bundles.
+  //   - static { this.ecmp = bla }
+  //   - static #_ = this.ecmp = bla
+  const staticIndicatorRegex = /static\s+(\{|#[_\d]+\s+=)/;
+
+  await ng('build');
+  await expectFileToExist('dist/test-project/main.js');
+  const mainContent = await readFile('dist/test-project/main.js');
+
+  // TODO: This default cause can be removed in the future when Safari v15
+  // is longer included in the default browserlist configuration of CLI apps.
+  if (staticIndicatorRegex.test(mainContent)) {
+    throw new Error(unexpectedStaticFieldErrorMessage);
+  }
+
+  await writeFile('.browserslistrc', 'last 1 chrome version');
+
+  await ng('build');
+  await expectFileToExist('dist/test-project/main.js');
+  const mainContentChromeLatest = await readFile('dist/test-project/main.js');
+
+  if (!staticIndicatorRegex.test(mainContentChromeLatest)) {
+    throw new Error('Expected static fields to be used when Safari <=v15 is not targeted.');
+  }
+
+  await writeFile('.browserslistrc', 'Safari <=15');
+
+  await ng('build');
+  await expectFileToExist('dist/test-project/main.js');
+  const mainContentSafari15Explicit = await readFile('dist/test-project/main.js');
+
+  if (staticIndicatorRegex.test(mainContentSafari15Explicit)) {
+    throw new Error(unexpectedStaticFieldErrorMessage);
+  }
+}