diff --git a/apisix/plugins/proxy-rewrite.lua b/apisix/plugins/proxy-rewrite.lua
index c7c37114990f..c678b5957ee6 100644
--- a/apisix/plugins/proxy-rewrite.lua
+++ b/apisix/plugins/proxy-rewrite.lua
@@ -48,7 +48,7 @@ local schema = {
         host = {
             description = "new host for upstream",
             type        = "string",
-            pattern     = "^[0-9a-zA-Z-.]+$",
+            pattern     = [[^[0-9a-zA-Z-.]+(:\d{1,5})?$]],
         },
         scheme = {
             description = "new scheme for upstream",
diff --git a/t/plugin/proxy-rewrite.t b/t/plugin/proxy-rewrite.t
index a7430109e686..58f0ffdcb6f8 100644
--- a/t/plugin/proxy-rewrite.t
+++ b/t/plugin/proxy-rewrite.t
@@ -1297,3 +1297,79 @@ GET /test?new_uri=hello
 hello world
 --- no_error_log
 [error]
+
+
+
+=== TEST 44: host with port
+--- config
+    location /t {
+        content_by_lua_block {
+            local plugin = require("apisix.plugins.proxy-rewrite")
+            local ok, err = plugin.check_schema({
+                host = 'apisix.iresty.com:6443',
+            })
+            if not ok then
+                ngx.say(err)
+            end
+
+            ngx.say("done")
+        }
+    }
+--- request
+GET /t
+--- response_body
+done
+--- no_error_log
+[error]
+
+
+
+=== TEST 45: set route(rewrite host with port)
+--- config
+    location /t {
+        content_by_lua_block {
+            local t = require("lib.test_admin").test
+            local code, body = t('/apisix/admin/routes/1',
+                 ngx.HTTP_PUT,
+                 [[{
+                        "methods": ["GET"],
+                        "plugins": {
+                            "proxy-rewrite": {
+                                "uri": "/uri",
+                                "host": "test.com:6443"
+                            }
+                        },
+                        "upstream": {
+                            "nodes": {
+                                "127.0.0.1:1980": 1
+                            },
+                            "type": "roundrobin"
+                        },
+                        "uri": "/hello"
+                }]]
+                )
+
+            if code >= 300 then
+                ngx.status = code
+            end
+            ngx.say(body)
+        }
+    }
+--- request
+GET /t
+--- response_body
+passed
+--- no_error_log
+[error]
+
+
+
+=== TEST 46: rewrite host with port
+--- request
+GET /hello
+--- response_body
+uri: /uri
+host: test.com:6443
+x-real-ip: 127.0.0.1
+--- no_error_log
+[error]