diff --git a/.changes/unreleased/Fixes-20220413-151735.yaml b/.changes/unreleased/Fixes-20220413-151735.yaml
new file mode 100644
index 00000000000..cdca821dc6a
--- /dev/null
+++ b/.changes/unreleased/Fixes-20220413-151735.yaml
@@ -0,0 +1,7 @@
+kind: Fixes
+body: Relax minimum supported version of MarkupSafe
+time: 2022-04-13T15:17:35.055274145-03:00
+custom:
+  Author: adamantike
+  Issue: "4745"
+  PR: "5039"
diff --git a/core/setup.py b/core/setup.py
index cf82825d1d1..5fda3cfcdf3 100644
--- a/core/setup.py
+++ b/core/setup.py
@@ -52,7 +52,7 @@
     ],
     install_requires=[
         'Jinja2==2.11.3',
-        'MarkupSafe==2.0.1',
+        'MarkupSafe>=0.23,<2.1',
         'agate>=1.6,<1.6.4',
         'click>=7.0,<9',
         'colorama>=0.3.9,<0.4.5',