diff --git a/Libraries/Animated/AnimatedImplementation.js b/Libraries/Animated/AnimatedImplementation.js
index f483d0a63f3647..84c47e36a1580f 100644
--- a/Libraries/Animated/AnimatedImplementation.js
+++ b/Libraries/Animated/AnimatedImplementation.js
@@ -556,7 +556,7 @@ type AnimatedNumeric =
   | AnimatedAddition
   | AnimatedDiffClamp
   | AnimatedDivision
-  | AnimatedInterpolation
+  | AnimatedInterpolation<number>
   | AnimatedModulo
   | AnimatedMultiplication
   | AnimatedSubtraction
diff --git a/Libraries/Animated/NativeAnimatedHelper.js b/Libraries/Animated/NativeAnimatedHelper.js
index e303128751b6e1..e97a10d262ebba 100644
--- a/Libraries/Animated/NativeAnimatedHelper.js
+++ b/Libraries/Animated/NativeAnimatedHelper.js
@@ -359,7 +359,9 @@ function validateStyles(styles: {[key: string]: ?number, ...}): void {
   }
 }
 
-function validateInterpolation(config: InterpolationConfigType): void {
+function validateInterpolation<OutputT: number | string>(
+  config: InterpolationConfigType<OutputT>,
+): void {
   for (const key in config) {
     if (!isSupportedInterpolationParam(key)) {
       throw new Error(
diff --git a/Libraries/Animated/animations/SpringAnimation.js b/Libraries/Animated/animations/SpringAnimation.js
index 471fe50216cd50..e02ed31872daa7 100644
--- a/Libraries/Animated/animations/SpringAnimation.js
+++ b/Libraries/Animated/animations/SpringAnimation.js
@@ -44,7 +44,7 @@ export type SpringAnimationConfig = {
         ...
       }
     | AnimatedColor
-    | AnimatedInterpolation,
+    | AnimatedInterpolation<number>,
   overshootClamping?: boolean,
   restDisplacementThreshold?: number,
   restSpeedThreshold?: number,
@@ -67,7 +67,7 @@ export type SpringAnimationConfig = {
 
 export type SpringAnimationConfigSingle = {
   ...AnimationConfig,
-  toValue: number | AnimatedValue | AnimatedInterpolation,
+  toValue: number,
   overshootClamping?: boolean,
   restDisplacementThreshold?: number,
   restSpeedThreshold?: number,
@@ -90,7 +90,7 @@ class SpringAnimation extends Animation {
   _startPosition: number;
   _lastPosition: number;
   _fromValue: number;
-  _toValue: any;
+  _toValue: number;
   _stiffness: number;
   _damping: number;
   _mass: number;
diff --git a/Libraries/Animated/animations/TimingAnimation.js b/Libraries/Animated/animations/TimingAnimation.js
index 859a5755f254ff..94c4b3a4b8361b 100644
--- a/Libraries/Animated/animations/TimingAnimation.js
+++ b/Libraries/Animated/animations/TimingAnimation.js
@@ -36,7 +36,7 @@ export type TimingAnimationConfig = $ReadOnly<{
     | AnimatedValueXY
     | RgbaValue
     | AnimatedColor
-    | AnimatedInterpolation,
+    | AnimatedInterpolation<number>,
   easing?: (value: number) => number,
   duration?: number,
   delay?: number,
@@ -44,7 +44,7 @@ export type TimingAnimationConfig = $ReadOnly<{
 
 export type TimingAnimationConfigSingle = $ReadOnly<{
   ...AnimationConfig,
-  toValue: number | AnimatedValue | AnimatedInterpolation,
+  toValue: number,
   easing?: (value: number) => number,
   duration?: number,
   delay?: number,
@@ -62,7 +62,7 @@ function easeInOut() {
 class TimingAnimation extends Animation {
   _startTime: number;
   _fromValue: number;
-  _toValue: any;
+  _toValue: number;
   _duration: number;
   _delay: number;
   _easing: (value: number) => number;
diff --git a/Libraries/Animated/nodes/AnimatedAddition.js b/Libraries/Animated/nodes/AnimatedAddition.js
index 409db6e4d6b7b3..b311b39a6606fc 100644
--- a/Libraries/Animated/nodes/AnimatedAddition.js
+++ b/Libraries/Animated/nodes/AnimatedAddition.js
@@ -38,7 +38,9 @@ class AnimatedAddition extends AnimatedWithChildren {
     return this._a.__getValue() + this._b.__getValue();
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Animated/nodes/AnimatedDiffClamp.js b/Libraries/Animated/nodes/AnimatedDiffClamp.js
index 629e04cc68113f..61b167c2fcba57 100644
--- a/Libraries/Animated/nodes/AnimatedDiffClamp.js
+++ b/Libraries/Animated/nodes/AnimatedDiffClamp.js
@@ -38,7 +38,9 @@ class AnimatedDiffClamp extends AnimatedWithChildren {
     super.__makeNative(platformConfig);
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Animated/nodes/AnimatedDivision.js b/Libraries/Animated/nodes/AnimatedDivision.js
index 1dcd4622ac135d..3d77e2de6453e7 100644
--- a/Libraries/Animated/nodes/AnimatedDivision.js
+++ b/Libraries/Animated/nodes/AnimatedDivision.js
@@ -54,7 +54,9 @@ class AnimatedDivision extends AnimatedWithChildren {
     return a / b;
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Animated/nodes/AnimatedInterpolation.js b/Libraries/Animated/nodes/AnimatedInterpolation.js
index dac38a30a18662..ee5ea21946241c 100644
--- a/Libraries/Animated/nodes/AnimatedInterpolation.js
+++ b/Libraries/Animated/nodes/AnimatedInterpolation.js
@@ -23,9 +23,9 @@ import type {PlatformConfig} from '../AnimatedPlatformConfig';
 
 type ExtrapolateType = 'extend' | 'identity' | 'clamp';
 
-export type InterpolationConfigType = $ReadOnly<{
+export type InterpolationConfigType<OutputT: number | string> = $ReadOnly<{
   inputRange: $ReadOnlyArray<number>,
-  outputRange: $ReadOnlyArray<number> | $ReadOnlyArray<string>,
+  outputRange: $ReadOnlyArray<OutputT>,
   easing?: (input: number) => number,
   extrapolate?: ExtrapolateType,
   extrapolateLeft?: ExtrapolateType,
@@ -38,14 +38,14 @@ const linear = (t: number) => t;
  * Very handy helper to map input ranges to output ranges with an easing
  * function and custom behavior outside of the ranges.
  */
-function createInterpolation(
-  config: InterpolationConfigType,
-): (input: number) => number | string {
+function createInterpolation<OutputT: number | string>(
+  config: InterpolationConfigType<OutputT>,
+): (input: number) => OutputT {
   if (config.outputRange && typeof config.outputRange[0] === 'string') {
-    return createInterpolationFromStringOutputRange(config);
+    return (createInterpolationFromStringOutputRange((config: any)): any);
   }
 
-  const outputRange: Array<number> = (config.outputRange: any);
+  const outputRange: $ReadOnlyArray<number> = (config.outputRange: any);
 
   const inputRange = config.inputRange;
 
@@ -87,7 +87,7 @@ function createInterpolation(
     );
 
     const range = findRange(input, inputRange);
-    return interpolate(
+    return (interpolate(
       input,
       inputRange[range],
       inputRange[range + 1],
@@ -96,7 +96,7 @@ function createInterpolation(
       easing,
       extrapolateLeft,
       extrapolateRight,
-    );
+    ): any);
   };
 }
 
@@ -195,7 +195,7 @@ const stringShapeRegex = /[+-]?(?:\d+\.?\d*|\.\d+)(?:[eE][+-]?\d+)?/g;
  *   -45deg                  // values with units
  */
 function createInterpolationFromStringOutputRange(
-  config: InterpolationConfigType,
+  config: InterpolationConfigType<string>,
 ): (input: number) => string {
   let outputRange: Array<string> = (config.outputRange: any);
   invariant(outputRange.length >= 2, 'Bad output range');
@@ -299,17 +299,19 @@ function checkInfiniteRange(name: string, arr: $ReadOnlyArray<number>) {
   );
 }
 
-class AnimatedInterpolation extends AnimatedWithChildren {
+class AnimatedInterpolation<
+  OutputT: number | string,
+> extends AnimatedWithChildren {
   // Export for testing.
   static __createInterpolation: (
-    config: InterpolationConfigType,
-  ) => (input: number) => number | string = createInterpolation;
+    config: InterpolationConfigType<OutputT>,
+  ) => (input: number) => OutputT = createInterpolation;
 
   _parent: AnimatedNode;
-  _config: InterpolationConfigType;
-  _interpolation: (input: number) => number | string;
+  _config: InterpolationConfigType<OutputT>;
+  _interpolation: (input: number) => OutputT;
 
-  constructor(parent: AnimatedNode, config: InterpolationConfigType) {
+  constructor(parent: AnimatedNode, config: InterpolationConfigType<OutputT>) {
     super();
     this._parent = parent;
     this._config = config;
@@ -330,7 +332,9 @@ class AnimatedInterpolation extends AnimatedWithChildren {
     return this._interpolation(parentValue);
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<NewOutputT: number | string>(
+    config: InterpolationConfigType<NewOutputT>,
+  ): AnimatedInterpolation<NewOutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
@@ -343,7 +347,7 @@ class AnimatedInterpolation extends AnimatedWithChildren {
     super.__detach();
   }
 
-  __transformDataType(range: Array<any>): Array<any> {
+  __transformDataType(range: $ReadOnlyArray<OutputT>): Array<any> {
     return range.map(NativeAnimatedHelper.transformDataType);
   }
 
@@ -355,9 +359,6 @@ class AnimatedInterpolation extends AnimatedWithChildren {
     return {
       inputRange: this._config.inputRange,
       // Only the `outputRange` can contain strings so we don't need to transform `inputRange` here
-      /* $FlowFixMe[incompatible-call] (>=0.38.0) - Flow error detected during
-       * the deployment of v0.38.0. To see the error, remove this comment and
-       * run flow */
       outputRange: this.__transformDataType(this._config.outputRange),
       extrapolateLeft:
         this._config.extrapolateLeft || this._config.extrapolate || 'extend',
diff --git a/Libraries/Animated/nodes/AnimatedModulo.js b/Libraries/Animated/nodes/AnimatedModulo.js
index 88663cc0e12426..bc3bc1b3ad2741 100644
--- a/Libraries/Animated/nodes/AnimatedModulo.js
+++ b/Libraries/Animated/nodes/AnimatedModulo.js
@@ -38,7 +38,9 @@ class AnimatedModulo extends AnimatedWithChildren {
     );
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Animated/nodes/AnimatedMultiplication.js b/Libraries/Animated/nodes/AnimatedMultiplication.js
index 9adb2570549703..419927b71f53dc 100644
--- a/Libraries/Animated/nodes/AnimatedMultiplication.js
+++ b/Libraries/Animated/nodes/AnimatedMultiplication.js
@@ -38,10 +38,11 @@ class AnimatedMultiplication extends AnimatedWithChildren {
     return this._a.__getValue() * this._b.__getValue();
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
-
   __attach(): void {
     this._a.__addChild(this);
     this._b.__addChild(this);
diff --git a/Libraries/Animated/nodes/AnimatedSubtraction.js b/Libraries/Animated/nodes/AnimatedSubtraction.js
index 3c8eb158fd05db..b3a9198c662baa 100644
--- a/Libraries/Animated/nodes/AnimatedSubtraction.js
+++ b/Libraries/Animated/nodes/AnimatedSubtraction.js
@@ -38,7 +38,9 @@ class AnimatedSubtraction extends AnimatedWithChildren {
     return this._a.__getValue() - this._b.__getValue();
   }
 
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Animated/nodes/AnimatedValue.js b/Libraries/Animated/nodes/AnimatedValue.js
index c829d3e5952513..c6f021467f8af7 100644
--- a/Libraries/Animated/nodes/AnimatedValue.js
+++ b/Libraries/Animated/nodes/AnimatedValue.js
@@ -219,7 +219,9 @@ class AnimatedValue extends AnimatedWithChildren {
    * Interpolates the value before updating the property, e.g. mapping 0-1 to
    * 0-10.
    */
-  interpolate(config: InterpolationConfigType): AnimatedInterpolation {
+  interpolate<OutputT: number | string>(
+    config: InterpolationConfigType<OutputT>,
+  ): AnimatedInterpolation<OutputT> {
     return new AnimatedInterpolation(this, config);
   }
 
diff --git a/Libraries/Components/ScrollView/ScrollViewStickyHeader.js b/Libraries/Components/ScrollView/ScrollViewStickyHeader.js
index a7b904b36643e3..ebd6f676def560 100644
--- a/Libraries/Components/ScrollView/ScrollViewStickyHeader.js
+++ b/Libraries/Components/ScrollView/ScrollViewStickyHeader.js
@@ -90,7 +90,7 @@ class ScrollViewStickyHeader extends React.Component<Props, State> {
   }
 
   updateTranslateListener(
-    translateY: AnimatedImplementation.Interpolation,
+    translateY: AnimatedNode,
     isFabric: boolean,
     offset: AnimatedDiffClamp | null,
   ) {
@@ -274,11 +274,11 @@ class ScrollViewStickyHeader extends React.Component<Props, State> {
                 .interpolate({
                   extrapolateLeft: 'clamp',
                   inputRange: [layoutY, layoutY + 1],
-                  outputRange: ([0, 1]: Array<number>),
+                  outputRange: [0, 1],
                 })
                 .interpolate({
                   inputRange: [0, 1],
-                  outputRange: ([0, -1]: Array<number>),
+                  outputRange: [0, -1],
                 }),
               -this.state.layoutHeight,
               0,