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enhancement: support other classes of structural variations #4

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zhilongjia opened this issue Apr 10, 2021 · 4 comments
Open

enhancement: support other classes of structural variations #4

zhilongjia opened this issue Apr 10, 2021 · 4 comments
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enhancement New feature or request

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@zhilongjia
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zhilongjia commented Apr 10, 2021

It will be great if it can show a custom track, like the UCSC genome browser.

Updated:
My goal is to check whether SV break an enhancer or not. Currently, it is not easy to get the location of a certain SV (using a mouse pointer). Thank you.

although it has a custom default track already, another track to show where is the SV segment among this default track will show genes nearby, which is important to the SV.

As an SV may disrupt an enhancer, so it will great to make an (column of) enhancer-centred view, besides the gene-centred view.

@flekschas
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It will be great if it can show a custom track, like the UCSC genome browser.

I am working on a feature to allow you to customize the entire view but you will have to use the HiGlass/Resgen(https://resgen.io) ecosystem.

Could you specify what kind of track you would like to load? At the moment you can at least already browse a custom bed track. This might already help you correlate SV with enhancers.

Currently, it is not easy to get the location of a certain SV.

Can you clarify? Navigating to a certain location is simple. Or do you mean something else?

@flekschas flekschas added the enhancement New feature or request label Apr 10, 2021
@zhilongjia
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zhilongjia commented Apr 11, 2021

I also made some update about my question.

Currently, it is not easy to get the location of a certain SV.

if a SV is within a custom track, it will be difficult to know the exact location of the SV.

If the custom track on the left is used only to show the SV itself, the nearby genes of the SV will be not shown. Thank you.

@flekschas
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I think I get your request. Supporting the structural variations-aware manner would indeed be cool. Unfortunately, I can't give you any time lines as this would be a pretty involved feature.

@flekschas flekschas changed the title enhancement: a custom track to show the input range enhancement: support other classes of structural variations Apr 11, 2021
@zhilongjia
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Showing genomic features, like structural variations, is great. Here a quick way is to use the input of users, not to load structural variations from a public database as the structural variations are relatively sparse in the genome. Thank you.

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