diff --git a/src/cmd/go/internal/work/security.go b/src/cmd/go/internal/work/security.go
index 270a34e9c7cf7..88504be6cd6b4 100644
--- a/src/cmd/go/internal/work/security.go
+++ b/src/cmd/go/internal/work/security.go
@@ -59,7 +59,10 @@ var validCompilerFlags = []*lazyregexp.Regexp{
 	re(`-f(no-)builtin-[a-zA-Z0-9_]*`),
 	re(`-f(no-)?common`),
 	re(`-f(no-)?constant-cfstrings`),
+	re(`-fdebug-prefix-map=([^@]+)=([^@]+)`),
 	re(`-fdiagnostics-show-note-include-stack`),
+	re(`-ffile-prefix-map=([^@]+)=([^@]+)`),
+	re(`-fno-canonical-system-headers`),
 	re(`-f(no-)?eliminate-unused-debug-types`),
 	re(`-f(no-)?exceptions`),
 	re(`-f(no-)?fast-math`),
@@ -114,6 +117,7 @@ var validCompilerFlags = []*lazyregexp.Regexp{
 	re(`-mthumb(-interwork)?`),
 	re(`-mthreads`),
 	re(`-mwindows`),
+	re(`-no-canonical-prefixes`),
 	re(`--param=ssp-buffer-size=[0-9]*`),
 	re(`-pedantic(-errors)?`),
 	re(`-pipe`),
diff --git a/src/cmd/go/testdata/script/cgo_suspect_flag_force_external.txt b/src/cmd/go/testdata/script/cgo_suspect_flag_force_external.txt
index d555278865baf..6dc30bedb9e9c 100644
--- a/src/cmd/go/testdata/script/cgo_suspect_flag_force_external.txt
+++ b/src/cmd/go/testdata/script/cgo_suspect_flag_force_external.txt
@@ -55,6 +55,32 @@ stderr preferlinkext
 env CGO_CFLAGS=-fprofile-instr-generate
 go build -x -n -o dummy.exe ./usesInternalCgo
 stderr preferlinkext
+
+# The -fdebug-prefix-map=path is permitted for internal linking.
+env CGO_CFLAGS=-fdebug-prefix-map=/some/sandbox/execroot/workspace=/tmp/new
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+env CGO_CFLAGS=-fdebug-prefix-map=/Users/someone/.cache/bazel/_bazel_someone/3fa7e4650c43657ead684537951f49e2/sandbox/linux-sandbox/10/execroot/rules_go_static=.
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+# The -ffile-prefix-map=path is permitted for internal linking too.
+env CGO_CFLAGS=-ffile-prefix-map=/Users/someone/.cache/bazel/_bazel_someone/3fa7e4650c43657ead684537951f49e2/sandbox/linux-sandbox/10/execroot/rules_go_static/bazel-out/aarch64-fastbuild-ST-b33d65c724e6/bin/external/io_bazel_rules_go/stdlib_=.
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+# Verifying that -fdebug-prefix-map=path, -ffile-prefix-map, -no-canonical-prefixes
+# and -fno-canonical-systemd-headers are permitted for internal linking.
+env CGO_CFLAGS=-fdebug-prefix-map=old=/tmp/new
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+env CGO_CFLAGS=-ffile-prefix-map=/Users/someone/_11233/things=new
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+env CGO_CFLAGS=-no-canonical-prefixes
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
+env CGO_CFLAGS=-fno-canonical-system-headers
+go build -x -n -o dummy.exe ./usesInternalCgo
+! stderr preferlinkext
 env CGO_CFLAGS=
 
 [short] skip