diff --git a/.kokoro/build.sh b/.kokoro/build.sh
index 69a53cf0..85db638c 100755
--- a/.kokoro/build.sh
+++ b/.kokoro/build.sh
@@ -41,7 +41,7 @@ python3 -m pip install --upgrade --quiet nox
 python3 -m nox --version
 
 # If this is a continuous build, send the test log to the FlakyBot.
-# See https://github.com/googleapis/repo-automation-bots/tree/master/packages/flakybot.
+# See https://github.com/googleapis/repo-automation-bots/tree/main/packages/flakybot.
 if [[ $KOKORO_BUILD_ARTIFACTS_SUBDIR = *"continuous"* ]]; then
   cleanup() {
     chmod +x $KOKORO_GFILE_DIR/linux_amd64/flakybot
diff --git a/.kokoro/test-samples-impl.sh b/.kokoro/test-samples-impl.sh
index 311a8d54..8a324c9c 100755
--- a/.kokoro/test-samples-impl.sh
+++ b/.kokoro/test-samples-impl.sh
@@ -80,7 +80,7 @@ for file in samples/**/requirements.txt; do
     EXIT=$?
 
     # If this is a periodic build, send the test log to the FlakyBot.
-    # See https://github.com/googleapis/repo-automation-bots/tree/master/packages/flakybot.
+    # See https://github.com/googleapis/repo-automation-bots/tree/main/packages/flakybot.
     if [[ $KOKORO_BUILD_ARTIFACTS_SUBDIR = *"periodic"* ]]; then
       chmod +x $KOKORO_GFILE_DIR/linux_amd64/flakybot
       $KOKORO_GFILE_DIR/linux_amd64/flakybot
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 8c63e9f2..02a5fb7a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -218,7 +218,7 @@ might break the hypothetical usecase of downloading a blob marked with
 - Modify file not found test to look for the correct error message
 - Harden tests so they can run with debug logging statements
 - Add Appveyor support. ([#40](https://github.com/googleapis/google-resumable-media-python/pull/40))
-- Mark the version in `master` as `.dev1`.
+- Mark the version in `main` as `.dev1`.
 
 
 ## 0.3.1
diff --git a/README.rst b/README.rst
index a698bd8a..8feae1dd 100644
--- a/README.rst
+++ b/README.rst
@@ -31,4 +31,4 @@ License
 
 Apache 2.0 - See `the LICENSE`_ for more information.
 
-.. _the LICENSE: https://github.com/googleapis/google-resumable-media-python/blob/master/LICENSE
+.. _the LICENSE: https://github.com/googleapis/google-resumable-media-python/blob/main/LICENSE
diff --git a/docs/conf.py b/docs/conf.py
index 3896205f..c16787e3 100644
--- a/docs/conf.py
+++ b/docs/conf.py
@@ -64,7 +64,7 @@
 # source_encoding = 'utf-8-sig'
 
 # The main toctree document.
-master_doc = "index"
+root_doc = "index"
 
 # General information about the project.
 project = u"google-resumable-media"
@@ -266,7 +266,7 @@
 #  author, documentclass [howto, manual, or own class]).
 latex_documents = [
     (
-        master_doc,
+        root_doc,
         "google-resumable-media.tex",
         u"google-resumable-media Documentation",
         author,
@@ -301,7 +301,7 @@
 # (source start file, name, description, authors, manual section).
 man_pages = [
     (
-        master_doc,
+        root_doc,
         "google-resumable-media",
         u"google-resumable-media Documentation",
         [author],
@@ -320,7 +320,7 @@
 #  dir menu entry, description, category)
 texinfo_documents = [
     (
-        master_doc,
+        root_doc,
         "google-resumable-media",
         u"google-resumable-media Documentation",
         author,
diff --git a/owlbot.py b/owlbot.py
index 0cf20644..e9ed0b7c 100644
--- a/owlbot.py
+++ b/owlbot.py
@@ -21,4 +21,16 @@
     r'value: "docs-staging-v2-staging"'
 )
 
+
+# Remove the replacements below once https://github.com/googleapis/synthtool/pull/1188 is merged
+
+# Update googleapis/repo-automation-bots repo to main in .kokoro/*.sh files
+s.replace(".kokoro/*.sh", "repo-automation-bots/tree/master", "repo-automation-bots/tree/main")
+
+s.replace(
+    "docs/conf.py",
+    "master_doc",
+    "root_doc",
+)
+
 s.shell.run(["nox", "-s", "blacken"], hide_output=False)