diff --git a/docs/releasenotes/10.1.0.rst b/docs/releasenotes/10.1.0.rst
index 78c52380c67..af995dc15b4 100644
--- a/docs/releasenotes/10.1.0.rst
+++ b/docs/releasenotes/10.1.0.rst
@@ -58,3 +58,9 @@ Added support for DDS 8-bit color indexed images
 ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
 
 Support has been added to read PALETTEINDEXED8 DDS files as P mode images.
+
+Support reading signed 8-bit YCbCr TIFF images
+^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+
+TIFF images with unsigned integer data, 8 bits per sample and a photometric
+interpretation of YCbCr can now be read.
diff --git a/src/PIL/TiffImagePlugin.py b/src/PIL/TiffImagePlugin.py
index 96de03a3e17..dabf8dbfb5f 100644
--- a/src/PIL/TiffImagePlugin.py
+++ b/src/PIL/TiffImagePlugin.py
@@ -251,6 +251,8 @@
     (II, 5, (1,), 1, (8, 8, 8, 8, 8, 8), (0, 0)): ("CMYK", "CMYKXX"),
     (MM, 5, (1,), 1, (8, 8, 8, 8, 8, 8), (0, 0)): ("CMYK", "CMYKXX"),
     (II, 5, (1,), 1, (16, 16, 16, 16), ()): ("CMYK", "CMYK;16L"),
+    (II, 6, (1,), 1, (8,), ()): ("L", "L"),
+    (MM, 6, (1,), 1, (8,), ()): ("L", "L"),
     # JPEG compressed images handled by LibTiff and auto-converted to RGBX
     # Minimal Baseline TIFF requires YCbCr images to have 3 SamplesPerPixel
     (II, 6, (1,), 1, (8, 8, 8), ()): ("RGB", "RGBX"),