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@pinellolab

Pinello Lab

Massachusetts General Hospital/Harvard Medical School

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  1. STREAM STREAM Public

    STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of single-cell data

    Jupyter Notebook 173 46

  2. CRISPResso2 CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    Python 268 92

  3. haystack_bio haystack_bio Public

    Haystack: Epigenetic Variability and Transcription Factor Motifs Analysis Pipeline

    HTML 45 11

  4. CRISPR-SURF CRISPR-SURF Public

    Python 15 3

  5. PrimeDesign PrimeDesign Public

    Software tool for the flexible design of pegRNAs and ngRNAs for prime editing!

    Python 22 7

  6. MotifRaptor MotifRaptor Public

    Explore the effect of genetic variants on transcription factor binding sites

    Python 8 2

Repositories

Showing 10 of 53 repositories
  • CRISPR-millipede-target Public

    Calculate the enrichment scores of CRISPR alleles and variants from direct target amplicon-sequencing data using Bayesian linear regression model "millipede".

    pinellolab/CRISPR-millipede-target’s past year of commit activity
    Python 1 AGPL-3.0 0 0 0 Updated Sep 17, 2024
  • pyrovelocity Public

    𝒫robabilistic modeling of RNA velocity ⬱

    pinellolab/pyrovelocity’s past year of commit activity
    Python 40 AGPL-3.0 5 11 19 Updated Sep 17, 2024
  • CRISPRme Public
    pinellolab/CRISPRme’s past year of commit activity
    Python 17 8 5 0 Updated Sep 17, 2024
  • CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    pinellolab/CRISPResso2’s past year of commit activity
    Python 268 92 29 4 Updated Sep 17, 2024
  • EPInformer Public

    code to run EPInformer for gene expression prediction and gene-enhancer links prioritization

    pinellolab/EPInformer’s past year of commit activity
    Jupyter Notebook 22 4 0 0 Updated Sep 15, 2024
  • CRISPR-Correct Public

    Perform CRISPR guide mapping and analysis that considers protospace self-editing and surrogate sensor sequences. Self-editing aware mapping takes a hamming-distance approach unbiased by expectations in editing patterns.

    pinellolab/CRISPR-Correct’s past year of commit activity
    Python 1 AGPL-3.0 0 2 0 Updated Sep 10, 2024
  • CRISPR-CLEAR-data Public

    Notebooks used to generate the figures and analyses in CRISPR-CLEAR manuscript.

    pinellolab/CRISPR-CLEAR-data’s past year of commit activity
    Jupyter Notebook 0 0 0 0 Updated Sep 9, 2024
  • DNA-Diffusion Public

    🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

    pinellolab/DNA-Diffusion’s past year of commit activity
    Python 357 49 8 11 Updated Sep 6, 2024
  • pinellolab/CRISPR-SURF’s past year of commit activity
    Python 15 AGPL-3.0 3 4 0 Updated Sep 4, 2024
  • CRISPR-millipede-helper Public

    Helper utility function for running CRISPR-millipede pipelines

    pinellolab/CRISPR-millipede-helper’s past year of commit activity
    Python 0 0 0 0 Updated Aug 29, 2024

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