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Antoine Vandecrème
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Nov 29, 2022
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<?xml version='1.0' encoding='UTF-8' standalone='no'?> | ||
<sbml xmlns="http://www.sbml.org/sbml/level2/version4" level="2" metaid="ea71b239_15b6_4fa3_a76f_dd6c414eede6" version="4"> | ||
<model id="MODEL1212210000" metaid="f4425bc4_80db_4c1c_b889_aae600e0ce20" name="Smith2013 - Regulation of Insulin Signalling by Oxidative Stress"> | ||
<listOfFunctionDefinitions> | ||
<functionDefinition id="function_1" metaid="_0b927bb6_7666_4bab_9a62_1bb488a2950b" name="Function for R1f_1"> | ||
<math xmlns="http://www.w3.org/1998/Math/MathML"> | ||
<lambda> | ||
<bvar> | ||
<ci> InR </ci> | ||
</bvar> | ||
<bvar> | ||
<ci> Ins </ci> | ||
</bvar> | ||
<bvar> | ||
<ci> cellsurface </ci> | ||
</bvar> | ||
<bvar> | ||
<ci> extracellular </ci> | ||
</bvar> | ||
<bvar> | ||
<ci> k1 </ci> | ||
</bvar> | ||
<apply> | ||
<times/> | ||
<ci> k1 </ci> | ||
<ci> Ins </ci> | ||
<ci> extracellular </ci> | ||
<ci> InR </ci> | ||
<ci> cellsurface </ci> | ||
</apply> | ||
</lambda> | ||
</math> | ||
</functionDefinition> | ||
</listOfFunctionDefinitions> | ||
<listOfCompartments> | ||
<compartment constant="true" id="extracellular" metaid="_33c764a6_3a3f_4ef0_8617_010e61aaadc6" name="extracellular" sboTerm="SBO:0000290" size="8.3E-12" spatialDimensions="3"> | ||
</compartment> | ||
<compartment constant="true" id="cellsurface" metaid="_3998f93a_7adc_4437_90cb_86503740c79e" name="cellsurface" outside="extracellular" sboTerm="SBO:0000290" size="6.4E-14" spatialDimensions="3"> | ||
</compartment> | ||
<compartment constant="true" id="cytoplasm" metaid="_546b89ee_5e8b_4791_875c_73de58897f5e" name="cytoplasm" outside="cellsurface" sboTerm="SBO:0000290" size="1.65E-11" spatialDimensions="3"> | ||
</compartment> | ||
</listOfCompartments> | ||
<listOfSpecies> | ||
<species boundaryCondition="true" compartment="extracellular" constant="true" hasOnlySubstanceUnits="false" id="Ins" initialAmount="0" metaid="_820723ff_e05b_49d4_b9bd_b025befd02dc" name="Ins"> | ||
</species> | ||
<species boundaryCondition="false" compartment="cellsurface" constant="false" hasOnlySubstanceUnits="false" id="InR" initialAmount="90000" metaid="d8602ba9_77a8_4307_ab2d_280bbcc14b67" name="InR"> | ||
</species> | ||
<species boundaryCondition="false" compartment="cellsurface" constant="false" hasOnlySubstanceUnits="false" id="Ins_InR" initialAmount="0" metaid="_9672349d_f3af_4c17_8def_526d82171d04" name="Ins_InR"> | ||
</species> | ||
</listOfSpecies> | ||
<listOfParameters> | ||
<parameter constant="true" id="k1" metaid="_2ad1244a_ce86_42ed_9222_df283a1c56a5" name="k1" value="2E-5"/> | ||
</listOfParameters> | ||
<listOfReactions> | ||
<reaction id="R1f" metaid="b644817b_aa91_4732_9b17_f83803035b63" name="R1f" reversible="false"> | ||
<listOfReactants> | ||
<speciesReference metaid="_652747b2_354c_407c_9dee_9680991fa150" species="Ins" stoichiometry="1"/> | ||
<speciesReference metaid="_725a5142_9442_4c37_908f_aeea73cdae7d" species="InR" stoichiometry="1"/> | ||
</listOfReactants> | ||
<listOfProducts> | ||
<speciesReference metaid="cc7fe296_cb4a_401f_ac8c_64cedf7f36d2" species="Ins_InR" stoichiometry="1"/> | ||
</listOfProducts> | ||
<listOfModifiers> | ||
<modifierSpeciesReference metaid="_0d4998c7_4bc9_4fa7_85b8_9fa7250d6151" species="InR"/> | ||
<modifierSpeciesReference metaid="a8a2b586_05fe_478f_a9e7_66a5ff911afe" species="Ins"/> | ||
</listOfModifiers> | ||
<kineticLaw metaid="_1d9b134e_3620_4ad0_8872_400169c862ca"> | ||
<math xmlns="http://www.w3.org/1998/Math/MathML"> | ||
<apply> | ||
<ci> function_1 </ci> | ||
<ci> InR </ci> | ||
<ci> Ins </ci> | ||
<ci> cellsurface </ci> | ||
<ci> extracellular </ci> | ||
<ci> k1 </ci> | ||
</apply> | ||
</math> | ||
</kineticLaw> | ||
</reaction> | ||
</listOfReactions> | ||
</model> | ||
</sbml> |
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